0	10	Inhibition	Inhibition	NNP
11	13	of	of	IN
14	27	transcription	transcription	NN
28	35	factors	factor	NNS
36	45	belonging	belong	VBG
46	48	to	to	TO
49	52	the	the	DT
53	65	rel/NF-kappa	rel/nf-kappa	NN
66	67	B	B	NNP
68	74	family	family	NN
75	77	by	by	IN
78	79	a	a	DT
80	93	transdominant	transdominant	JJ
94	102	negative	negative	JJ
103	109	mutant	mutant	NN
109	110	.	.	.

112	115	The	the	DT
116	120	KBF1	kbf1	NN
121	127	factor	factor	NN
127	128	,	,	,
129	134	which	which	WDT
135	140	binds	bind	VBZ
141	143	to	to	TO
144	147	the	the	DT
148	156	enhancer	enhancer	NN
157	158	A	a	NN
159	166	located	located	JJ
167	169	in	in	IN
170	173	the	the	DT
174	182	promoter	promoter	NN
183	185	of	of	IN
186	189	the	the	DT
190	195	mouse	mouse	NN
196	199	MHC	MHC	NNP
200	205	class	class	NN
206	207	I	i	CD
208	212	gene	gene	NN
213	218	H-2Kb	H-2Kb	NNP
218	219	,	,	,
220	222	is	be	VBZ
223	240	indistinguishable	indistinguishable	JJ
241	245	from	from	IN
246	249	the	the	DT
250	253	p50	p50	NN
254	257	DNA	dna	NN
258	265	binding	binding	NN
266	273	subunit	subunit	NN
274	276	of	of	IN
277	280	the	the	DT
281	294	transcription	transcription	NN
295	301	factor	factor	NN
302	310	NF-kappa	NF-kappa	NNP
311	312	B	B	NNP
312	313	,	,	,
314	319	which	which	WDT
320	329	regulates	regulate	VBZ
330	331	a	a	DT
332	338	series	series	NN
339	341	of	of	IN
342	347	genes	gene	NNS
348	356	involved	involve	VBN
357	359	in	in	IN
360	366	immune	immune	JJ
367	370	and	and	CC
371	383	inflammatory	inflammatory	JJ
384	393	responses	response	NNS
393	394	.	.	.

395	398	The	the	DT
399	407	KBF1/p50	kbf1/p50	NN
408	414	factor	factor	NN
415	420	binds	bind	VBZ
421	423	as	as	IN
424	425	a	a	DT
426	435	homodimer	homodimer	NN
436	439	but	but	CC
440	443	can	can	MD
444	448	also	also	RB
449	453	form	form	VB
454	466	heterodimers	heterodimer	NNS
467	471	with	with	IN
472	475	the	the	DT
476	484	products	product	NNS
485	487	of	of	IN
488	493	other	other	JJ
494	501	members	member	NNS
502	504	of	of	IN
505	508	the	the	DT
509	513	same	same	JJ
514	520	family	family	NN
520	521	,	,	,
522	526	like	like	IN
527	530	the	the	DT
531	536	c-rel	c-rel	NN
537	540	and	and	CC
541	546	v-rel	v-rel	NN
547	548	(	(	(
548	563	proto)oncogenes	proto)oncogene	NNS
563	564	.	.	.

565	568	The	the	DT
569	581	dimerization	dimerization	NN
582	588	domain	domain	NN
589	591	of	of	IN
592	600	KBF1/p50	KBF1/p50	NNP
601	603	is	be	VBZ
604	613	contained	contain	VBN
614	621	between	between	IN
622	627	amino	amino	NN
628	633	acids	acid	NNS
634	637	201	201	CD
638	641	and	and	CC
642	645	367	367	CD
645	646	.	.	.

647	648	A	a	DT
649	655	mutant	mutant	NN
656	658	of	of	IN
659	667	KBF1/p50	KBF1/p50	NNP
668	669	(	(	(
669	674	delta	delta	SYM
675	677	SP	SP	NNP
677	678	)	)	)
678	679	,	,	,
680	686	unable	unable	JJ
687	689	to	to	TO
690	694	bind	bind	VB
695	697	to	to	TO
698	701	DNA	DNA	NNP
702	705	but	but	CC
706	710	able	able	JJ
711	713	to	to	TO
714	718	form	form	VB
719	724	homo-	homo-	JJ
725	727	or	or	CC
728	740	heterodimers	heterodimer	NNS
740	741	,	,	,
742	745	has	have	VBZ
746	750	been	be	VBN
751	762	constructed	construct	VBN
762	763	.	.	.

764	768	This	this	DT
769	776	protein	protein	NN
777	784	reduces	reduce	VBZ
785	787	or	or	CC
788	797	abolishes	abolish	VBZ
798	800	in	in	FW
801	806	vitro	vitro	FW
807	810	the	the	DT
811	814	DNA	dna	NN
815	822	binding	binding	NN
823	831	activity	activity	NN
832	834	of	of	IN
835	844	wild-type	wild-type	JJ
845	853	proteins	protein	NNS
854	856	of	of	IN
857	860	the	the	DT
861	865	same	same	JJ
866	872	family	family	NN
873	874	(	(	(
874	882	KBF1/p50	KBF1/p50	NNP
882	883	,	,	,
884	886	c-	c-	NN
887	890	and	and	CC
891	896	v-rel	v-rel	NN
896	897	)	)	)
897	898	.	.	.

899	903	This	this	DT
904	910	mutant	mutant	NN
911	915	also	also	RB
916	925	functions	function	VBZ
926	928	in	in	FW
929	933	vivo	vivo	FW
934	936	as	as	IN
937	938	a	a	DT
939	951	trans-acting	trans-acting	JJ
952	960	dominant	dominant	JJ
961	969	negative	negative	JJ
970	979	regulator	regulator	NN
979	980	:	:	:
981	984	the	the	DT
985	1000	transcriptional	transcriptional	JJ
1001	1013	inducibility	inducibility	NN
1014	1016	of	of	IN
1017	1020	the	the	DT
1021	1024	HIV	HIV	NNP
1025	1029	long	long	JJ
1030	1038	terminal	terminal	JJ
1039	1045	repeat	repeat	NN
1046	1047	(	(	(
1047	1052	which	which	WDT
1053	1061	contains	contain	VBZ
1062	1065	two	two	CD
1066	1075	potential	potential	JJ
1076	1084	NF-kappa	NF-kappa	NNP
1085	1086	B	B	NNP
1087	1094	binding	binding	NN
1095	1100	sites	site	NNS
1100	1101	)	)	)
1102	1104	by	by	IN
1105	1112	phorbol	phorbol	NN
1113	1118	ester	ester	NN
1119	1120	(	(	(
1120	1123	PMA	PMA	NNP
1123	1124	)	)	)
1125	1127	is	be	VBZ
1128	1137	inhibited	inhibit	VBN
1138	1142	when	when	WRB
1143	1145	it	it	PRP
1146	1148	is	be	VBZ
1149	1163	co-transfected	co-transfecte	VBN
1164	1168	into	into	IN
1169	1173	CD4+	cd4+	JJ
1174	1175	T	t	NN
1176	1181	cells	cell	NNS
1182	1186	with	with	IN
1187	1190	the	the	DT
1191	1196	delta	delta	NN
1197	1199	SP	SP	NNP
1200	1206	mutant	mutant	NN
1206	1207	.	.	.

1208	1217	Similarly	similarly	RB
1218	1221	the	the	DT
1222	1227	basal	basal	JJ
1228	1230	as	as	RB
1231	1235	well	well	RB
1236	1238	as	as	IN
1239	1242	TNF	TNF	NNP
1243	1245	or	or	CC
1246	1257	IL1-induced	il1-induced	JJ
1258	1266	activity	activity	NN
1267	1269	of	of	IN
1270	1273	the	the	DT
1274	1277	MHC	MHC	NNP
1278	1283	class	class	NN
1284	1285	I	i	CD
1286	1291	H-2Kb	H-2Kb	NNP
1292	1300	promoter	promoter	NN
1301	1304	can	can	MD
1305	1307	be	be	VB
1308	1317	inhibited	inhibit	VBN
1318	1320	by	by	IN
1321	1325	this	this	DT
1326	1332	mutant	mutant	NN
1333	1335	in	in	IN
1336	1339	two	two	CD
1340	1349	different	different	JJ
1350	1354	cell	cell	NN
1355	1360	lines	line	NNS
1360	1361	.	.	.

1362	1367	These	these	DT
1368	1375	results	result	NNS
1376	1386	constitute	constitute	VBP
1387	1390	the	the	DT
1391	1396	first	first	JJ
1397	1403	formal	formal	JJ
1404	1417	demonstration	demonstration	NN
1418	1422	that	that	IN
1423	1428	these	these	DT
1429	1434	genes	gene	NNS
1435	1438	are	be	VBP
1439	1448	regulated	regulate	VBN
1449	1451	by	by	IN
1452	1459	members	member	NNS
1460	1462	of	of	IN
1463	1466	the	the	DT
1467	1479	rel/NF-kappa	rel/nf-kappa	NN
1480	1481	B	B	NNP
1482	1488	family	family	NN
1488	1489	.	.	.