0 8 NF-kappa NF-kappa NNP 9 10 B B NNP 11 19 activity activity NN 20 22 in in IN 23 24 T t NN 25 30 cells cell NNS 31 37 stably stably RB 38 48 expressing express VBG 49 52 the the DT 53 56 Tax Tax NNP 57 64 protein protein NN 65 67 of of IN 68 73 human human JJ 74 75 T t NN 76 80 cell cell NN 81 93 lymphotropic lymphotropic JJ 94 99 virus virus NN 100 104 type type NN 105 107 I. i. IN 109 112 The the DT 113 119 effect effect NN 120 122 of of IN 123 135 constitutive constitutive JJ 136 139 Tax Tax NNP 140 150 expression expression NN 151 153 on on IN 154 157 the the DT 158 169 interaction interaction NN 170 172 of of IN 173 181 NF-kappa NF-kappa NNP 182 183 B B NNP 184 188 with with IN 189 192 its its PRP$ 193 204 recognition recognition NN 205 213 sequence sequence NN 214 217 and and CC 218 220 on on IN 221 229 NF-kappa NF-kappa NNP 230 241 B-dependent b-dependent JJ 242 246 gene gene NN 247 257 expression expression NN 258 261 was be VBD 262 270 examined examine VBN 271 273 in in IN 274 275 T t NN 276 284 lymphoid lymphoid JJ 285 291 Jurkat Jurkat NNP 292 296 cell cell NN 297 302 lines line NNS 303 304 ( ( ( 304 307 19D 19d NN 308 311 and and CC 312 314 9J 9j NN 314 315 ) ) ) 316 322 stably stably RB 323 334 transformed transform VBN 335 339 with with IN 340 341 a a DT 342 345 Tax Tax NNP 346 356 expression expression NN 357 363 vector vector NN 363 364 . . . 365 368 Tax Tax NNP 369 379 expressing express VBG 380 381 T t NN 382 386 cell cell NN 387 392 lines line NNS 393 402 contained contain VBD 403 404 a a DT 405 417 constitutive constitutive JJ 418 423 level level NN 424 426 of of IN 427 435 NF-kappa NF-kappa NNP 436 437 B B NNP 438 445 binding binding NN 446 454 activity activity NN 454 455 , , , 456 466 detectable detectable JJ 467 469 by by IN 470 478 mobility mobility NN 479 484 shift shift NN 485 490 assay assay NN 491 494 and and CC 495 497 uv uv NN 498 511 cross-linking cross-linking NN 512 517 using use VBG 518 519 a a DT 520 531 palindromic palindromic JJ 532 540 NF-kappa NF-kappa NNP 541 542 B B NNP 543 548 probe probe NN 549 559 homologous homologous JJ 560 562 to to TO 563 566 the the DT 567 577 interferon interferon NN 578 582 beta beta NN 583 588 PRDII PRDII NNP 589 593 site site NN 593 594 . . . 595 597 In in IN 598 604 Jurkat Jurkat NNP 605 608 and and CC 609 615 NC2.10 NC2.10 NNP 616 625 induction induction NN 626 630 with with IN 631 638 phorbol phorbol NN 639 645 esters ester NNS 646 654 resulted result VBD 655 657 in in IN 658 661 the the DT 662 672 appearance appearance NN 673 675 of of IN 676 679 new new JJ 680 683 DNA dna NN 684 691 binding binding NN 692 700 proteins protein NNS 701 703 of of IN 704 706 85 85 CD 706 707 , , , 708 710 75 75 CD 710 711 , , , 712 715 and and CC 716 718 54 54 CD 719 722 kDa kda NN 722 723 , , , 724 731 whereas whereas IN 732 734 in in IN 735 738 Tax Tax NNP 739 749 expressing expressing NN 750 755 cells cell NNS 756 759 the the DT 760 766 85-kDa 85-kda JJ 767 774 protein protein NN 775 778 and and CC 779 780 a a DT 781 787 92-kDa 92-kda JJ 788 791 DNA dna NN 792 799 binding binding NN 800 807 protein protein NN 808 812 were be VBD 813 827 constitutively constitutively RB 828 835 induced induce VBN 835 836 . . . 837 847 Expression expression NN 848 850 of of IN 851 854 Tax Tax NNP 855 862 protein protein NN 863 865 in in IN 866 869 19D 19d NN 870 873 and and CC 874 876 9J 9j NN 877 885 resulted result VBD 886 888 in in IN 889 902 transcription transcription NN 903 905 of of IN 906 909 the the DT 910 920 endogenous endogenous JJ 921 929 NF-kappa NF-kappa NNP 930 941 B-dependent b-dependent JJ 942 964 granulocyte-macrophage granulocyte-macrophage JJ 965 971 colony colony NN 972 983 stimulating stimulating NN 984 990 factor factor NN 991 995 gene gene NN 996 999 and and CC 1000 1009 increased increase VBD 1010 1015 basal basal JJ 1016 1021 level level NN 1022 1032 expression expression NN 1033 1035 of of IN 1036 1047 transfected transfecte VBN 1048 1056 NF-kappa NF-kappa NNP 1057 1068 B-regulated b-regulated JJ 1069 1078 promoters promoter NNS 1078 1079 . . . 1080 1091 Nonetheless nonetheless RB 1092 1105 transcription transcription NN 1106 1108 of of IN 1109 1113 both both CC 1114 1117 the the DT 1118 1128 endogenous endogenous JJ 1129 1132 and and CC 1133 1136 the the DT 1137 1148 transfected transfecte VBN 1149 1153 gene gene NN 1154 1157 was be VBD 1158 1167 inducible inducible JJ 1168 1170 by by IN 1171 1174 PMA PMA NNP 1175 1184 treatment treatment NN 1184 1185 . . . 1186 1189 Tax Tax NNP 1190 1200 expression expression NN 1201 1203 in in IN 1204 1210 Jurkat Jurkat NNP 1211 1212 T t NN 1213 1218 cells cell NNS 1219 1222 may may MD 1223 1228 alter alter VB 1229 1232 the the DT 1233 1246 stoichiometry stoichiometry NN 1247 1249 of of IN 1250 1258 NF-kappa NF-kappa NNP 1259 1260 B B NNP 1261 1264 DNA DNA NNP 1265 1272 binding binding NN 1273 1281 proteins protein NNS 1282 1285 and and CC 1286 1290 thus thus RB 1291 1297 change change VB 1298 1301 the the DT 1302 1312 expression expression NN 1313 1315 of of IN 1316 1324 NF-kappa NF-kappa NNP 1325 1336 B-regulated b-regulated JJ 1337 1346 promoters promoter NNS 1346 1347 . . .