0	10	Activation	Activation	NNP
11	13	of	of	IN
14	21	pp90rsk	pp90rsk	NN
22	25	and	and	CC
26	31	early	early	JJ
32	38	growth	growth	NN
39	49	response-1	response-1	NN
50	54	gene	gene	NN
55	65	expression	expression	NN
66	68	by	by	IN
69	77	pokeweed	pokeweed	NN
78	85	mitogen	mitogen	NN
86	88	in	in	IN
89	94	human	human	JJ
95	96	B	B	NNP
97	102	cells	cell	NNS
102	103	.	.	.

105	108	The	the	DT
109	116	present	present	JJ
117	124	studies	study	NNS
125	129	have	have	VBP
130	138	examined	examine	VBN
139	142	the	the	DT
143	150	effects	effect	NNS
151	153	of	of	IN
154	162	pokeweed	pokeweed	NN
163	170	mitogen	mitogen	NN
171	172	(	(	(
172	175	PWM	PWM	NNP
175	176	)	)	)
177	179	on	on	IN
180	183	the	the	DT
184	193	induction	induction	NN
194	196	of	of	IN
197	202	early	early	JJ
203	209	growth	growth	NN
210	220	response-1	response-1	NN
221	225	gene	gene	NN
226	227	(	(	(
227	232	EGR-1	egr-1	NN
232	233	)	)	)
234	236	in	in	IN
237	243	normal	normal	JJ
244	249	human	human	JJ
250	251	B	b	NN
252	257	cells	cell	NNS
257	258	.	.	.

259	262	PWM	PWM	NNP
263	272	regulates	regulate	VBZ
273	278	EGR-1	egr-1	NN
279	283	gene	gene	NN
284	294	expression	expression	NN
295	297	by	by	IN
298	302	both	both	CC
303	318	transcriptional	transcriptional	JJ
319	322	and	and	CC
323	343	post-transcriptional	post-transcriptional	JJ
344	354	mechanisms	mechanism	NNS
354	355	.	.	.

356	365	Transient	transient	JJ
366	378	transfection	transfection	NN
379	385	assays	assay	NNS
386	390	with	with	IN
391	396	EGR-1	egr-1	NN
397	405	promoter	promoter	NN
406	415	fragments	fragment	NNS
416	422	linked	link	VBN
423	425	to	to	TO
426	429	the	the	DT
430	445	chloramphenicol	chloramphenicol	NN
446	463	acetyltransferase	acetyltransferase	NN
464	465	(	(	(
465	468	CAT	CAT	NNP
468	469	)	)	)
470	474	gene	gene	NN
475	487	demonstrated	demonstrate	VBD
488	492	that	that	IN
493	496	PWM	PWM	NNP
497	504	induced	induce	VBD
505	510	EGR-1	egr-1	NN
511	524	transcription	transcription	NN
525	527	is	be	VBZ
528	537	conferred	confer	VBN
538	540	by	by	IN
541	544	the	the	DT
545	549	CArG	CArG	NNP
550	555	motif	motif	NN
556	557	(	(	(
557	558	C	C	NNP
559	567	C[AT]6GG	C[AT]6GG	NNP
567	568	)	)	)
569	571	in	in	IN
572	575	the	the	DT
576	581	EGR-1	egr-1	NN
582	590	promoter	promoter	NN
590	591	.	.	.

592	595	The	the	DT
596	603	results	result	NNS
604	611	further	further	RB
612	624	demonstrated	demonstrate	VBD
625	628	the	the	DT
629	639	activation	activation	NN
640	642	of	of	IN
643	645	S6	S6	NNP
646	652	kinase	kinase	NNP
653	654	(	(	(
654	661	pp90rsk	pp90rsk	NN
661	662	)	)	)
662	663	,	,	,
664	673	evidenced	evidence	VBN
674	676	by	by	IN
677	692	phosphorylation	phosphorylation	NN
693	695	of	of	IN
696	698	S6	S6	NNP
699	702	and	and	CC
703	708	serum	serum	NN
709	717	response	response	NN
718	724	factor	factor	NN
725	726	(	(	(
726	729	SRF	SRF	NNP
729	730	)	)	)
731	739	peptides	peptide	NNS
739	740	,	,	,
741	743	in	in	IN
744	747	PWM	PWM	NNP
748	755	treated	treated	JJ
756	757	B	B	NNP
758	763	cells	cell	NNS
763	764	.	.	.

765	770	Taken	take	VBN
771	779	together	together	RB
779	780	,	,	,
781	786	these	these	DT
787	795	findings	finding	NNS
796	803	suggest	suggest	VBP
804	808	that	that	IN
809	812	PWM	PWM	NNP
813	815	is	be	VBZ
816	820	able	able	JJ
821	823	to	to	TO
824	832	initiate	initiate	VB
833	835	an	an	DT
836	852	intracytoplasmic	intracytoplasmic	JJ
853	863	signalling	signalling	NN
864	871	cascade	cascade	NN
872	875	and	and	CC
876	881	EGR-1	egr-1	NN
882	891	induction	induction	NN
892	894	in	in	IN
895	901	normal	normal	JJ
902	907	human	human	JJ
908	909	B	b	NN
910	915	cells	cell	NNS
915	916	.	.	.