0	4	IL-7	IL-7	NNP
5	18	reconstitutes	reconstitute	VBZ
19	27	multiple	multiple	JJ
28	35	aspects	aspect	NNS
36	38	of	of	IN
39	53	v-Abl-mediated	v-abl-mediated	JJ
54	63	signaling	signaling	NN
63	64	.	.	.

66	69	The	the	DT
70	79	mechanism	mechanism	NN
80	82	by	by	IN
83	88	which	which	WDT
89	94	early	early	JJ
95	103	lymphoid	lymphoid	JJ
104	109	cells	cell	NNS
110	113	are	be	VBP
114	125	selectively	selectively	RB
126	137	transformed	transform	VBN
138	140	by	by	IN
141	146	v-Abl	v-abl	NN
147	149	is	be	VBZ
150	159	currently	currently	RB
160	167	unknown	unknown	JJ
167	168	.	.	.

169	177	Previous	previous	JJ
178	185	studies	study	NNS
186	190	have	have	VBP
191	196	shown	show	VBN
197	209	constitutive	constitutive	JJ
210	220	activation	activation	NN
221	223	of	of	IN
224	228	IL-4	il-4	NN
229	232	and	and	CC
233	237	IL-7	il-7	NN
238	247	signaling	signaling	NN
248	256	pathways	pathway	NNS
256	257	,	,	,
258	260	as	as	IN
261	269	measured	measure	VBN
270	272	by	by	IN
273	283	activation	activation	NN
284	286	of	of	IN
287	292	Janus	Janus	NNP
293	300	protein	protein	NN
301	307	kinase	kinase	NNP
308	309	(	(	(
309	314	JAK)1	JAK)1	NNP
314	315	,	,	,
316	320	JAK3	JAK3	NNP
320	321	,	,	,
322	327	STAT5	STAT5	NNP
327	328	,	,	,
329	332	and	and	CC
333	338	STAT6	STAT6	NNP
338	339	,	,	,
340	342	in	in	IN
343	348	pre-B	pre-b	JJ
349	354	cells	cell	NNS
355	366	transformed	transform	VBN
367	369	by	by	IN
370	375	v-Abl	v-abl	NN
375	376	.	.	.

377	379	To	to	TO
380	389	determine	determine	VB
390	397	whether	whether	IN
398	408	activation	activation	NN
409	411	of	of	IN
412	417	these	these	DT
418	426	cytokine	cytokine	NN
427	436	signaling	signaling	NN
437	445	pathways	pathway	NNS
446	448	by	by	IN
449	454	v-Abl	v-abl	NN
455	457	is	be	VBZ
458	467	important	important	JJ
468	470	in	in	IN
471	474	the	the	DT
475	483	cellular	cellular	JJ
484	490	events	event	NNS
491	498	induced	induce	VBN
499	501	by	by	IN
502	505	the	the	DT
506	513	Abelson	Abelson	NNP
514	520	murine	murine	JJ
521	529	leukemia	leukemia	NN
530	535	virus	virus	NN
535	536	,	,	,
537	540	the	the	DT
541	548	effects	effect	NNS
549	551	of	of	IN
552	556	IL-4	il-4	NN
557	560	and	and	CC
561	565	IL-7	il-7	NN
566	568	on	on	IN
569	574	pre-B	pre-b	JJ
575	580	cells	cell	NNS
581	592	transformed	transform	VBN
593	597	with	with	IN
598	599	a	a	DT
600	621	temperature-sensitive	temperature-sensitive	JJ
622	627	v-Abl	v-abl	NN
628	634	mutant	mutant	NN
635	639	were	be	VBD
640	648	examined	examine	VBN
648	649	.	.	.

650	657	Whereas	whereas	IN
658	662	IL-4	il-4	NN
663	666	had	have	VBD
667	673	little	little	JJ
674	676	or	or	CC
677	679	no	no	DT
680	686	effect	effect	NN
686	687	,	,	,
688	692	IL-7	IL-7	NNP
693	700	delayed	delay	VBD
701	705	both	both	CC
706	709	the	the	DT
710	719	apoptosis	apoptosis	NN
720	723	and	and	CC
724	728	cell	cell	NN
729	734	cycle	cycle	NN
735	741	arrest	arrest	NN
742	746	that	that	WDT
747	752	occur	occur	VBP
753	757	upon	upon	IN
758	763	v-Abl	v-abl	NN
764	770	kinase	kinase	NNP
771	783	inactivation	inactivation	NN
783	784	.	.	.

785	789	IL-7	IL-7	NNP
790	794	also	also	RB
795	802	delayed	delay	VBD
803	806	the	the	DT
807	816	decreases	decrease	NNS
817	819	in	in	IN
820	823	the	the	DT
824	830	levels	level	NNS
831	833	of	of	IN
834	839	c-Myc	c-myc	NN
839	840	,	,	,
841	846	Bcl-2	bcl-2	NN
846	847	,	,	,
848	851	and	and	CC
852	858	Bcl-xL	Bcl-xL	NNP
859	863	that	that	WDT
864	869	occur	occur	VBP
870	874	upon	upon	IN
875	879	loss	loss	NN
880	882	of	of	IN
883	888	v-Abl	v-abl	NN
889	895	kinase	kinase	NNP
896	904	activity	activity	NN
904	905	.	.	.

906	910	IL-7	IL-7	NNP
911	914	did	do	VBD
915	918	not	not	RB
919	927	maintain	maintain	VB
928	942	v-Abl-mediated	v-abl-mediated	JJ
943	958	differentiation	differentiation	NN
959	965	arrest	arrest	NN
966	968	of	of	IN
969	972	the	the	DT
973	978	pre-B	pre-b	JJ
979	984	cells	cell	NNS
984	985	,	,	,
986	988	as	as	IN
989	999	activation	activation	NN
1000	1002	of	of	IN
1003	1012	NF-kappaB	NF-kappaB	NNP
1013	1016	and	and	CC
1017	1020	RAG	RAG	NNP
1021	1025	gene	gene	NN
1026	1039	transcription	transcription	NN
1040	1043	was	be	VBD
1044	1054	unaffected	unaffected	JJ
1055	1057	by	by	IN
1058	1062	IL-7	IL-7	NNP
1062	1063	.	.	.

1064	1069	These	these	DT
1070	1077	results	result	NNS
1078	1086	identify	identify	VBP
1087	1088	a	a	DT
1089	1098	potential	potential	JJ
1099	1103	role	role	NN
1104	1107	for	for	IN
1108	1112	IL-7	il-7	NN
1113	1122	signaling	signaling	NN
1123	1131	pathways	pathway	NNS
1132	1134	in	in	IN
1135	1149	transformation	transformation	NN
1150	1152	by	by	IN
1153	1158	v-Abl	v-abl	NN
1159	1164	while	while	IN
1165	1178	demonstrating	demonstrate	VBG
1179	1183	that	that	IN
1184	1185	a	a	DT
1186	1197	combination	combination	NN
1198	1200	of	of	IN
1201	1205	IL-4	il-4	NN
1206	1209	and	and	CC
1210	1214	IL-7	il-7	NN
1215	1224	signaling	signaling	NN
1225	1231	cannot	cannot	MD
1232	1242	substitute	substitute	VB
1243	1246	for	for	IN
1247	1249	an	an	DT
1250	1256	active	active	JJ
1257	1262	v-Abl	v-abl	NN
1263	1269	kinase	kinase	NNP
1270	1272	in	in	IN
1273	1284	transformed	transform	VBN
1285	1290	pre-B	pre-b	JJ
1291	1296	cells	cell	NNS
1296	1297	.	.	.