0 14 Glucocorticoid glucocorticoid NN 15 23 receptor receptor NN 24 26 in in IN 27 35 patients patient NNS 36 40 with with IN 41 46 lupus lupus NN 47 56 nephritis nephritis NN 56 57 : : : 58 70 relationship relationship NN 71 78 between between IN 79 87 receptor receptor NN 88 94 levels level NNS 95 97 in in IN 98 109 mononuclear mononuclear JJ 110 120 leukocytes leukocyte NNS 121 124 and and CC 125 131 effect effect NN 132 134 of of IN 135 149 glucocorticoid glucocorticoid NN 150 157 therapy therapy NN 157 158 . . . 160 162 We we PRP 163 175 investigated investigate VBD 176 179 the the DT 180 188 clinical clinical JJ 189 201 significance significance NN 202 204 of of IN 205 219 glucocorticoid glucocorticoid NN 220 228 receptor receptor NN 229 242 determination determination NN 243 245 in in IN 246 248 20 20 CD 249 257 patients patient NNS 258 262 with with IN 263 271 systemic systemic JJ 272 277 lupus lupus NN 278 291 erythematosus erythematosus NN 292 293 ( ( ( 293 296 SLE sle NN 296 297 ) ) ) 298 301 who who WP 302 312 afterwards afterwards RB 313 322 developed develop VBD 323 332 nephrotic nephrotic JJ 333 341 syndrome syndrome NN 341 342 . . . 343 357 Glucocorticoid glucocorticoid NN 358 366 receptor receptor NN 367 381 concentrations concentration NNS 382 384 in in IN 385 396 mononuclear mononuclear JJ 397 407 leukocytes leukocyte NNS 408 409 ( ( ( 409 412 MNL MNL NNP 412 413 ) ) ) 414 416 in in IN 417 422 these these DT 423 431 patients patient NNS 432 436 were be VBD 437 447 comparable comparable JJ 448 452 with with IN 453 458 those those DT 459 461 in in IN 462 466 both both CC 467 472 other other JJ 473 481 patients patient NNS 482 486 with with IN 487 490 SLE SLE NNP 491 494 and and CC 495 502 healthy healthy JJ 503 510 persons person NNS 510 511 . . . 512 523 Improvement Improvement NNP 524 526 in in IN 527 534 urinary urinary JJ 535 542 protein protein NN 543 552 excretion excretion NN 553 556 and and CC 557 559 in in IN 560 567 disease disease NN 568 576 activity activity NN 576 577 , , , 578 583 which which WDT 584 587 was be VBD 588 594 scored score VBN 595 604 according accord VBG 605 607 to to TO 608 611 the the DT 612 615 SLE SLE NNP 616 623 Disease Disease NNP 624 632 Activity Activity NNP 633 638 Index Index NNP 639 645 system system NN 646 648 of of IN 649 652 the the DT 653 663 University University NNP 664 666 of of IN 667 674 Toronto Toronto NNP 674 675 , , , 676 683 closely closely RB 684 691 related related JJ 692 694 to to TO 695 698 the the DT 699 713 glucocorticoid glucocorticoid NN 714 722 receptor receptor NN 723 737 concentrations concentration NNS 738 740 in in IN 741 744 MNL MNL NNP 745 753 isolated isolate VBN 754 758 from from IN 759 762 the the DT 763 776 corresponding corresponding JJ 777 785 patients patient NNS 785 786 . . . 787 789 In in IN 790 797 summary summary NN 797 798 , , , 799 813 glucocorticoid glucocorticoid NN 814 822 receptor receptor NN 823 836 determination determination NN 837 839 in in IN 840 848 patients patient NNS 849 853 with with IN 854 859 lupus lupus NN 860 869 nephritis nephritis NN 870 873 may may MD 874 876 be be VB 877 878 a a DT 879 889 predictive predictive JJ 890 894 clue clue NN 895 898 for for IN 899 908 assessing assess VBG 909 923 responsiveness responsiveness NN 924 926 to to TO 927 941 glucocorticoid glucocorticoid NN 942 949 therapy therapy NN 949 950 . . .