0	10	Disruption	disruption	NN
11	13	of	of	IN
14	17	the	the	DT
18	23	human	human	JJ
24	27	SCL	scl	NN
28	33	locus	locus	NN
34	36	by	by	IN
37	38	“	``	``
38	50	illegitimate	illegitimate	JJ
50	51	”	''	''
52	59	V-(D)-J	V-(D)-J	NNP
60	71	recombinase	recombinase	NNP
72	80	activity	activity	NN
80	81	.	.	.

83	84	A	a	DT
85	91	fusion	fusion	NN
92	105	complementary	complementary	JJ
106	109	DNA	dna	NN
110	112	in	in	IN
113	116	the	the	DT
117	118	T	t	NN
119	123	cell	cell	NN
124	128	line	line	NN
129	134	HSB-2	hsb-2	NN
135	145	elucidates	elucidate	VBZ
146	147	a	a	DT
148	159	provocative	provocative	JJ
160	169	mechanism	mechanism	NN
170	173	for	for	IN
174	177	the	the	DT
178	188	disruption	disruption	NN
189	191	of	of	IN
192	195	the	the	DT
196	204	putative	putative	JJ
205	218	hematopoietic	hematopoietic	JJ
219	232	transcription	transcription	NN
233	239	factor	factor	NN
240	243	SCL	SCL	NNP
243	244	.	.	.

245	248	The	the	DT
249	255	fusion	fusion	NN
256	260	cDNA	cdna	NN
261	268	results	result	VBZ
269	273	from	from	IN
274	276	an	an	DT
277	289	interstitial	interstitial	JJ
290	298	deletion	deletion	NN
299	306	between	between	IN
307	308	a	a	DT
309	319	previously	previously	RB
320	327	unknown	unknown	JJ
328	333	locus	locus	NN
333	334	,	,	,
335	338	SIL	SIL	NNP
339	340	(	(	(
340	343	SCL	SCL	NNP
344	356	interrupting	interrupting	NN
357	362	locus	locus	NN
362	363	)	)	)
363	364	,	,	,
365	368	and	and	CC
369	372	the	the	DT
373	374	5	5	CD
374	375	’	'	SYM
376	388	untranslated	untranslated	JJ
389	395	region	region	NN
396	398	of	of	IN
399	402	SCL	SCL	NNP
402	403	.	.	.

404	411	Similar	similar	JJ
412	414	to	to	TO
415	419	1;14	1;14	CD
420	434	translocations	translocation	NNS
434	435	,	,	,
436	440	this	this	DT
441	449	deletion	deletion	NN
450	458	disrupts	disrupt	VBZ
459	462	the	the	DT
463	466	SCL	SCL	NNP
467	468	5	5	CD
468	469	’	'	SYM
470	480	regulatory	regulatory	JJ
481	487	region	region	NN
487	488	.	.	.

489	493	This	this	DT
494	499	event	event	NN
500	502	is	be	VBZ
503	511	probably	probably	RB
512	520	mediated	mediate	VBN
521	523	by	by	IN
524	531	V-(D)-J	v-(d)-j	JJ
532	543	recombinase	recombinase	NNP
544	552	activity	activity	NN
552	553	,	,	,
554	562	although	although	IN
563	570	neither	neither	DT
571	576	locus	locus	NN
577	579	is	be	VBZ
580	582	an	an	DT
583	597	immunoglobulin	immunoglobulin	NN
598	600	or	or	CC
601	602	a	a	DT
603	604	T	t	NN
605	609	cell	cell	NN
610	618	receptor	receptor	NN
618	619	.	.	.

620	623	Two	two	CD
624	629	other	other	JJ
630	631	T	t	NN
632	636	cell	cell	NN
637	642	lines	line	NNS
642	643	,	,	,
644	647	CEM	CEM	NNP
648	651	and	and	CC
652	656	RPMI	RPMI	NNP
657	661	8402	8402	CD
661	662	,	,	,
663	667	have	have	VBP
668	679	essentially	essentially	RB
680	689	identical	identical	JJ
690	699	deletions	deletion	NNS
699	700	.	.	.

701	705	Thus	thus	RB
705	706	,	,	,
707	709	in	in	IN
710	721	lymphocytes	lymphocyte	NNS
721	722	,	,	,
723	739	growth-affecting	growth-affecting	JJ
740	745	genes	gene	NNS
746	751	other	other	JJ
752	756	than	than	IN
757	763	immune	immune	JJ
764	773	receptors	receptor	NNS
774	778	risk	risk	NN
779	793	rearrangements	rearrangement	NNS
793	794	.	.	.