0 1 [ [ ( 1 7 Effect effect NN 8 10 of of IN 11 14 the the DT 15 22 regimen regimen NN 23 25 of of IN 26 42 kidney-tonifying kidney-tonifying NN 43 46 and and CC 47 62 qi-invigorating qi-invigorating NN 63 65 on on IN 66 71 aging age VBG 72 79 changes change NNS 80 82 of of IN 83 97 glucocorticoid glucocorticoid NN 98 106 receptor receptor NN 106 107 ] ] ) 109 112 The the DT 113 119 plasma plasma NN 120 128 cortisol cortisol NN 129 142 concentration concentration NN 143 146 and and CC 147 150 the the DT 151 156 sites site NNS 157 159 of of IN 160 174 glucocorticoid glucocorticoid NN 175 183 receptor receptor NN 184 185 ( ( ( 185 188 GCR GCR NNP 188 189 ) ) ) 190 192 in in IN 193 196 the the DT 197 207 peripheral peripheral JJ 208 219 lymphocytes lymphocyte NNS 220 224 were be VBD 225 233 measured measure VBN 234 236 in in IN 237 239 32 32 CD 240 247 healthy healthy JJ 248 252 aged aged JJ 253 260 persons person NNS 261 264 and and CC 265 267 13 13 CD 268 273 young young JJ 274 280 adults adult NNS 280 281 . . . 282 284 In in IN 285 291 animal animal NN 292 302 experiment experiment NN 302 303 , , , 304 307 GCR GCR NNP 308 310 of of IN 311 317 spleen spleen NN 318 329 lymphocytic lymphocytic JJ 330 334 cell cell NN 335 338 was be VBD 339 343 also also RB 344 352 measured measure VBN 353 355 in in IN 356 358 18 18 CD 359 363 aged aged JJ 364 368 rats rat NNS 369 372 and and CC 373 374 9 9 CD 375 380 young young JJ 381 385 rats rat NNS 385 386 . . . 387 390 The the DT 391 398 results result NNS 399 405 showed show VBD 406 410 that that IN 411 414 GCR GCR NNP 415 418 was be VBD 419 432 significantly significantly RB 433 438 lower low JJR 439 441 in in IN 442 445 the the DT 446 450 aged aged JJ 451 458 persons person NNS 459 461 or or CC 462 466 rats rat NNS 467 471 than than IN 472 476 that that DT 477 479 in in IN 480 483 the the DT 484 489 young young JJ 490 495 while while IN 496 499 the the DT 500 506 plasma plasma NN 507 515 cortisol cortisol NN 516 521 level level NN 522 525 did do VBD 525 528 n’t n't RB 529 535 change change VB 536 540 with with IN 541 546 aging aging NN 546 547 . . . 548 550 So so RB 551 553 we we PRP 554 559 think think VBP 560 564 that that IN 565 568 GCR GCR NNP 569 571 is be VBZ 572 576 more more RBR 577 586 sensitive sensitive JJ 587 591 than than IN 592 595 the the DT 596 602 plasma plasma NN 603 611 cortisol cortisol NN 612 617 level level NN 618 620 to to TO 621 628 reflect reflect VB 629 632 the the DT 633 638 aging aging NN 639 645 change change NN 646 648 of of IN 649 652 the the DT 653 660 adrenal adrenal JJ 661 667 cortex cortex NN 668 676 function function NN 676 677 . . . 678 683 After after IN 684 687 the the DT 688 697 treatment treatment NN 698 702 with with IN 703 706 the the DT 707 714 regimen regimen NN 715 717 of of IN 718 734 Kidney-tonifying kidney-tonifying NN 735 738 and and CC 739 754 Qi-invigorating qi-invigorating NN 754 755 , , , 756 759 the the DT 760 763 GCR gcr NN 764 766 of of IN 767 770 the the DT 771 775 aged aged JJ 776 783 persons person NNS 784 787 and and CC 788 792 rats rat NNS 793 796 was be VBD 797 805 enhanced enhance VBN 805 806 , , , 807 810 and and CC 811 813 in in IN 814 818 this this DT 819 822 way way NN 822 823 , , , 824 827 the the DT 828 836 function function NN 837 839 of of IN 840 843 the the DT 844 848 aged aged JJ 849 856 adrenal adrenal JJ 857 863 cortex cortex NN 864 867 was be VBD 868 876 improved improve VBN 876 877 . . .