0 10 Expression expression NN 11 13 of of IN 14 17 the the DT 18 27 chemokine chemokine NN 28 36 receptor receptor NN 37 46 BLR2/EBI1 blr2/ebi1 NN 47 49 is be VBZ 50 62 specifically specifically RB 63 77 transactivated transactivate VBN 78 80 by by IN 81 93 Epstein-Barr epstein-barr JJ 94 99 virus virus NN 100 107 nuclear nuclear JJ 108 115 antigen antigen NN 116 117 2 2 CD 117 118 . . . 120 122 In in IN 123 126 our our PRP$ 127 134 attempt attempt NN 135 137 to to TO 138 146 identify identify VB 147 156 chemokine chemokine NN 157 166 receptors receptor NNS 167 171 that that WDT 172 175 are be VBP 176 183 related relate VBN 184 186 to to TO 187 194 Burkitt Burkitt NNP 194 196 ’s 's POS 197 205 lymphoma lymphoma NN 206 214 receptor receptor NN 215 216 1 1 CD 217 218 ( ( ( 218 222 BLR1 blr1 NN 222 223 ) ) ) 224 227 and and CC 228 231 are be VBP 232 241 expressed express VBN 242 244 in in IN 245 254 activated activate VBN 255 266 lymphocytes lymphocyte NNS 267 269 we we PRP 270 274 used use VBD 275 281 RT-PCR RT-PCR NNP 282 291 resulting result VBG 292 294 in in IN 295 298 the the DT 299 308 isolation isolation NN 309 311 of of IN 312 313 a a DT 314 318 cDNA cdna NN 319 327 encoding encode VBG 328 329 a a DT 330 335 seven seven CD 336 349 transmembrane transmembrane NN 350 358 receptor receptor NN 359 365 termed term VBN 366 370 BLR2 blr2 NN 370 371 . . . 372 375 The the DT 376 383 protein protein NN 384 389 shows show VBZ 390 401 significant significant JJ 402 410 sequence sequence NN 411 423 similarities similarity NNS 424 426 to to TO 427 430 the the DT 431 437 family family NN 438 440 of of IN 441 450 G-protein G-protein NNP 451 458 coupled couple VBN 459 468 chemokine chemokine NN 469 478 receptors receptor NNS 479 482 and and CC 483 489 turned turn VBD 490 493 out out RP 494 496 to to TO 497 499 be be VB 500 509 identical identical JJ 510 512 to to TO 513 516 the the DT 517 525 recently recently RB 526 535 described describe VBN 536 544 receptor receptor NN 545 549 EBI1 ebi1 NN 549 550 . . . 551 559 Northern Northern NNP 560 564 blot blot NN 565 573 analysis analysis NN 574 582 revealed reveal VBD 583 587 that that IN 588 592 BLR2 BLR2 NNP 593 597 mRNA mRNA NNP 598 603 could could MD 604 606 be be VB 607 613 highly highly RB 614 624 stimulated stimulate VBN 625 627 in in IN 628 636 mitogen- mitogen- NN 637 640 and and CC 641 657 anti-CD3-treated anti-cd3-treated JJ 658 668 peripheral peripheral JJ 669 674 blood blood NN 675 686 lymphocytes lymphocyte NNS 686 687 . . . 688 701 BLR2-specific blr2-specific JJ 702 706 mRNA mRNA NNP 707 712 could could MD 713 715 be be VB 716 724 detected detect VBN 725 727 in in IN 728 731 all all DT 732 744 Epstein-Barr epstein-barr JJ 745 750 virus virus NN 751 759 positive positive JJ 760 761 B B NNP 762 766 cell cell NN 767 772 lines line NNS 772 773 . . . 774 776 We we PRP 777 781 show show VBP 782 786 that that IN 787 800 transcription transcription NN 801 803 of of IN 804 807 the the DT 808 812 BLR2 blr2 NN 813 817 gene gene NN 818 823 could could MD 824 826 be be VB 827 839 specifically specifically RB 840 847 induced induce VBN 848 850 in in IN 851 863 Epstein-Barr epstein-barr JJ 864 869 virus virus NN 870 878 negative negative JJ 879 881 BL BL NNP 882 884 41 41 CD 885 890 cells cell NNS 891 894 via via IN 895 912 estrogen-mediated estrogen-mediated JJ 913 923 activation activation NN 924 926 of of IN 927 939 Epstein-Barr epstein-barr JJ 940 945 virus virus NN 946 953 nuclear nuclear JJ 954 961 antigen antigen NN 962 963 2 2 CD 963 964 , , , 965 966 a a DT 967 970 key key JJ 971 980 regulator regulator NN 981 983 of of IN 984 989 viral viral JJ 990 993 and and CC 994 1002 cellular cellular JJ 1003 1008 genes gene NNS 1009 1011 in in IN 1012 1024 immortalized immortalize VBN 1025 1026 B B NNP 1027 1032 cells cell NNS 1032 1033 . . . 1034 1037 Our our PRP$ 1038 1042 data datum NNS 1043 1050 suggest suggest VBP 1051 1053 an an DT 1054 1065 involvement involvement NN 1066 1068 of of IN 1069 1073 BLR2 blr2 NN 1074 1076 in in IN 1077 1080 the the DT 1081 1091 regulation regulation NN 1092 1094 of of IN 1095 1104 migration migration NN 1105 1107 in in IN 1108 1117 activated activate VBN 1118 1129 lymphocytes lymphocyte NNS 1130 1133 and and CC 1134 1136 in in IN 1137 1142 viral viral JJ 1143 1155 pathogenesis pathogenesis NN 1155 1156 . . .