0	12	Epstein-Barr	epstein-barr	JJ
13	18	virus	virus	NN
19	26	nuclear	nuclear	JJ
27	34	antigen	antigen	NN
35	36	2	2	CD
37	40	and	and	CC
41	47	latent	latent	JJ
48	56	membrane	membrane	NN
57	64	protein	protein	NN
65	78	independently	independently	RB
79	92	transactivate	transactivate	VBP
93	96	p53	p53	NN
97	104	through	through	IN
105	114	induction	induction	NN
115	117	of	of	IN
118	127	NF-kappaB	NF-kappaB	NNP
128	136	activity	activity	NN
136	137	.	.	.

139	145	B-cell	b-cell	NN
146	161	immortalization	immortalization	NN
162	164	by	by	IN
165	177	Epstein-Barr	epstein-barr	JJ
178	183	virus	virus	NN
184	185	(	(	(
185	188	EBV	EBV	NNP
188	189	)	)	)
190	192	is	be	VBZ
193	202	dependent	dependent	JJ
203	205	on	on	IN
206	215	permanent	permanent	JJ
216	223	control	control	NN
224	226	of	of	IN
227	230	the	the	DT
231	239	cellular	cellular	JJ
240	249	processes	process	NNS
250	255	which	which	WDT
256	264	normally	normally	RB
265	273	regulate	regulate	VBP
274	278	cell	cell	NN
279	287	division	division	NN
288	291	and	and	CC
292	301	apoptosis	apoptosis	NN
301	302	,	,	,
303	312	functions	function	NNS
313	322	possessed	possess	VBN
323	325	by	by	IN
326	329	p53	p53	NN
330	332	in	in	IN
333	334	a	a	DT
335	341	number	number	NN
342	344	of	of	IN
345	351	normal	normal	JJ
352	356	cell	cell	NN
357	362	types	type	NNS
362	363	.	.	.

364	366	In	in	IN
367	374	studies	study	NNS
375	384	initiated	initiate	VBN
385	387	to	to	TO
388	396	evaluate	evaluate	VB
397	410	relationships	relationship	NNS
411	418	between	between	IN
419	422	EBV	EBV	NNP
423	429	latent	latent	JJ
430	435	genes	gene	NNS
436	439	and	and	CC
440	443	p53	p53	NN
443	444	,	,	,
445	448	p53	p53	NN
449	455	levels	level	NNS
456	460	were	be	VBD
461	466	found	find	VBN
467	469	to	to	TO
470	478	increase	increase	VB
479	492	approximately	approximately	RB
493	500	10-fold	10-fold	RB
501	502	4	4	CD
503	505	to	to	TO
506	507	5	5	CD
508	512	days	day	NNS
513	518	after	after	IN
519	522	EBV	EBV	NNP
523	532	infection	infection	NN
533	535	of	of	IN
536	544	purified	purify	VBN
545	552	resting	rest	VBG
553	558	human	human	JJ
559	560	B	B	NNP
561	566	cells	cell	NNS
566	567	;	;	:
568	571	the	the	DT
572	579	induced	induce	VBN
580	583	p53	p53	NN
584	587	was	be	VBD
588	605	transcriptionally	transcriptionally	RB
606	612	active	active	JJ
612	613	.	.	.

614	620	Latent	latent	JJ
621	629	membrane	membrane	NN
630	637	protein	protein	NN
638	639	1	1	CD
640	643	and	and	CC
643	644	,	,	,
645	647	to	to	TO
648	649	a	a	DT
650	656	lesser	less	JJR
657	663	extent	extent	NN
663	664	,	,	,
665	668	EBV	EBV	NNP
669	676	nuclear	nuclear	JJ
677	684	antigen	antigen	NN
685	686	2	2	CD
687	695	mediated	mediate	VBD
696	699	the	the	DT
700	708	increase	increase	NN
709	711	in	in	IN
712	715	p53	p53	NN
716	722	levels	level	NNS
723	726	via	via	IN
727	737	activation	activation	NN
738	740	of	of	IN
741	744	the	the	DT
745	754	NF-kappaB	NF-kappaB	NNP
755	768	transcription	transcription	NN
769	775	factor	factor	NN
775	776	.	.	.