0	5	Naive	naive	JJ
6	7	(	(	(
7	14	CD45RA+	cd45ra+	JJ
14	15	)	)	)
16	17	T	t	NN
18	29	lymphocytes	lymphocyte	NNS
30	33	are	be	VBP
34	38	more	more	RBR
39	48	sensitive	sensitive	JJ
49	51	to	to	TO
52	61	oxidative	oxidative	JJ
62	76	stress-induced	stress-induced	JJ
77	84	signals	signal	NNS
85	89	than	than	IN
90	96	memory	memory	NN
97	98	(	(	(
98	105	CD45RO+	cd45ro+	JJ
105	106	)	)	)
107	112	cells	cell	NNS
112	113	.	.	.

115	124	Formation	formation	NN
125	127	of	of	IN
128	136	reactive	reactive	JJ
137	143	oxygen	oxygen	NN
144	157	intermediates	intermediate	NNS
158	159	(	(	(
159	162	ROI	ROI	NNP
162	163	)	)	)
164	169	after	after	IN
170	179	oxidative	oxidative	JJ
180	186	stress	stress	NN
187	190	has	have	VBZ
191	195	been	be	VBN
196	201	shown	show	VBN
202	204	to	to	TO
205	207	be	be	VB
208	210	an	an	DT
211	221	activation	activation	NN
222	228	signal	signal	NN
229	232	for	for	IN
233	234	T	t	NN
235	246	lymphocytes	lymphocyte	NNS
246	247	,	,	,
248	252	e.g.	e.g.	FW
252	253	,	,	,
254	264	expression	expression	NN
265	267	of	of	IN
268	272	IL-2	il-2	NN
273	276	and	and	CC
277	280	its	its	PRP$
281	289	receptor	receptor	NN
290	293	are	be	VBP
294	301	induced	induce	VBN
301	302	.	.	.

303	308	These	these	DT
309	320	ROI-induced	roi-induced	JJ
321	328	effects	effect	NNS
329	332	can	can	MD
332	333	,	,	,
334	336	to	to	TO
337	338	a	a	DT
339	344	large	large	JJ
345	351	extent	extent	NN
351	352	,	,	,
353	355	be	be	VB
356	366	attributed	attribute	VBN
367	369	to	to	TO
370	373	the	the	DT
374	384	activation	activation	NN
385	387	of	of	IN
388	391	the	the	DT
392	405	transcription	transcription	NN
406	412	factor	factor	NN
413	422	NF-kappaB	nf-kappab	NN
422	423	.	.	.

424	427	Now	now	RB
428	430	we	we	PRP
431	435	have	have	VBP
436	444	examined	examine	VBN
445	452	whether	whether	IN
453	458	naive	naive	JJ
459	462	and	and	CC
463	469	memory	memory	NN
470	471	T	t	NN
472	483	lymphocytes	lymphocyte	NNS
484	490	differ	differ	VBP
491	493	in	in	IN
494	499	their	their	PRP$
500	511	sensitivity	sensitivity	NN
512	514	to	to	TO
515	527	ROI-mediated	roi-mediated	JJ
528	535	signals	signal	NNS
535	536	.	.	.

537	541	When	when	WRB
542	549	CD45RA+	cd45ra+	JJ
550	551	(	(	(
551	556	naive	naive	JJ
556	557	)	)	)
558	561	and	and	CC
562	569	CD45RO+	cd45ro+	JJ
570	571	(	(	(
571	577	memory	memory	NN
577	578	)	)	)
579	580	T	t	NN
581	592	lymphocytes	lymphocyte	NNS
593	597	were	be	VBD
598	606	directly	directly	RB
607	617	stimulated	stimulate	VBN
618	622	with	with	IN
623	627	H2O2	H2O2	NNP
627	628	,	,	,
629	638	NF-kappaB	NF-kappaB	NNP
639	646	nuclear	nuclear	JJ
647	660	translocation	translocation	NN
661	664	was	be	VBD
665	673	stronger	strong	JJR
674	676	in	in	IN
677	682	naive	naive	JJ
683	688	cells	cell	NNS
689	693	than	than	IN
694	696	in	in	IN
697	703	memory	memory	NN
704	709	cells	cell	NNS
710	713	and	and	CC
714	716	it	it	PRP
717	722	could	could	MD
723	725	be	be	VB
726	733	induced	induce	VBN
734	738	with	with	IN
739	744	lower	low	JJR
745	750	doses	dose	NNS
750	751	.	.	.

752	755	The	the	DT
756	767	composition	composition	NN
768	770	of	of	IN
771	774	the	the	DT
775	782	induced	induce	VBN
783	790	nuclear	nuclear	JJ
791	800	NF-kappaB	NF-kappaB	NNP
801	802	(	(	(
802	808	levels	level	NNS
809	811	of	of	IN
812	815	p50	p50	NN
816	819	and	and	CC
820	824	RelA	RelA	NNP
825	833	proteins	protein	NNS
833	834	)	)	)
835	838	was	be	VBD
839	846	similar	similar	JJ
847	849	in	in	IN
850	855	these	these	DT
856	860	cell	cell	NN
861	866	types	type	NNS
866	867	.	.	.

868	871	The	the	DT
872	881	magnitude	magnitude	NN
882	885	and	and	CC
886	894	kinetics	kinetic	NNS
895	897	of	of	IN
898	911	intracellular	intracellular	JJ
912	915	ROI	ROI	NNP
916	920	were	be	VBD
921	928	similar	similar	JJ
928	929	,	,	,
930	940	suggesting	suggest	VBG
941	945	that	that	IN
946	951	there	there	EX
952	956	were	be	VBD
957	959	no	no	DT
960	971	differences	difference	NNS
972	974	in	in	IN
975	986	ROI-forming	roi-forming	JJ
987	997	mechanisms	mechanism	NNS
998	1000	or	or	CC
1001	1014	antioxidative	antioxidative	JJ
1015	1025	capacities	capacity	NNS
1025	1026	.	.	.

1027	1030	The	the	DT
1031	1039	probable	probable	JJ
1040	1050	regulatory	regulatory	JJ
1051	1056	point	point	NN
1057	1060	was	be	VBD
1061	1064	the	the	DT
1065	1076	cytoplasmic	cytoplasmic	JJ
1077	1084	IkappaB	ikappab	NN
1085	1094	inhibitor	inhibitor	NN
1094	1095	:	:	:
1096	1098	in	in	IN
1099	1106	CD45RA+	cd45ra+	JJ
1107	1112	cells	cell	NNS
1112	1113	,	,	,
1114	1118	H2O2	H2O2	NNP
1119	1125	caused	cause	VBD
1126	1127	a	a	DT
1128	1132	more	more	RBR
1133	1141	profound	profound	JJ
1142	1152	depression	depression	NN
1153	1155	in	in	IN
1156	1159	the	the	DT
1160	1166	levels	level	NNS
1167	1169	of	of	IN
1170	1177	IkappaB	IkappaB	NNP
1178	1183	alpha	alpha	NN
1183	1184	.	.	.

1185	1190	These	these	DT
1191	1199	findings	finding	NNS
1200	1208	indicate	indicate	VBP
1209	1213	that	that	IN
1214	1215	T	t	NN
1216	1221	cells	cell	NNS
1222	1234	representing	represent	VBG
1235	1244	different	different	JJ
1245	1255	activation	activation	NN
1256	1262	and/or	and/or	CC
1263	1278	differentiation	differentiation	NN
1279	1285	stages	stage	NNS
1286	1289	can	can	MD
1290	1292	be	be	VB
1293	1307	differentially	differentially	RB
1308	1318	responsive	responsive	JJ
1319	1321	to	to	TO
1322	1334	ROI-mediated	roi-mediated	JJ
1335	1342	signals	signal	NNS
1342	1343	.	.	.