0	12	Differential	differential	JJ
13	22	induction	induction	NN
23	25	of	of	IN
26	36	interferon	interferon	NN
37	38	(	(	(
38	52	IFN)-inducible	ifn)-inducible	JJ
53	60	protein	protein	NN
61	63	10	10	CD
64	73	following	follow	VBG
74	89	differentiation	differentiation	NN
90	92	of	of	IN
93	94	a	a	DT
95	103	monocyte	monocyte	NN
103	104	,	,	,
105	115	macrophage	macrophage	NN
116	120	cell	cell	NN
121	128	lineage	lineage	NN
129	131	is	be	VBZ
132	139	related	related	JJ
140	142	to	to	TO
143	146	the	the	DT
147	154	changes	change	NNS
155	157	of	of	IN
158	165	nuclear	nuclear	JJ
166	174	proteins	protein	NNS
175	180	bound	bind	VBN
181	183	to	to	TO
184	187	IFN	ifn	NN
188	196	stimulus	stimulus	NN
197	205	response	response	NN
206	213	element	element	NN
214	217	and	and	CC
218	224	kappaB	kappab	NN
225	230	sites	site	NNS
230	231	.	.	.

233	235	We	we	PRP
236	244	examined	examine	VBD
245	254	chemokine	chemokine	NN
255	259	gene	gene	NN
260	270	expression	expression	NN
271	280	following	follow	VBG
281	284	the	the	DT
285	300	differentiation	differentiation	NN
301	303	of	of	IN
304	305	a	a	DT
306	314	monocyte	monocyte	NN
314	315	,	,	,
316	326	macrophage	macrophage	NN
327	331	cell	cell	NN
332	339	lineage	lineage	NN
339	340	.	.	.

341	344	The	the	DT
345	350	human	human	JJ
351	362	monoblastic	monoblastic	JJ
363	367	cell	cell	NN
368	372	line	line	NN
372	373	,	,	,
374	378	U937	U937	NNP
379	382	was	be	VBD
383	397	differentiated	differentiate	VBN
398	400	to	to	TO
401	412	macrophages	macrophage	NNS
413	415	by	by	IN
416	419	the	the	DT
420	429	treatment	treatment	NN
430	434	with	with	IN
435	441	either	either	CC
442	449	phorbol	phorbol	NN
450	462	12-myristate	12-myristate	NN
463	473	13-acetate	13-acetate	NN
474	475	(	(	(
475	478	PMA	PMA	NNP
478	479	)	)	)
479	480	,	,	,
481	489	retinoic	retinoic	JJ
490	494	acid	acid	NN
495	496	(	(	(
496	498	RA	RA	NNP
498	499	)	)	)
499	500	,	,	,
501	503	or	or	CC
504	511	vitamin	vitamin	NN
512	514	D3	D3	NNP
515	516	(	(	(
516	523	VitD3).	VitD3).	NNP
524	527	The	the	DT
528	532	gene	gene	NN
533	543	expression	expression	NN
544	546	of	of	IN
547	557	interferon	interferon	NN
558	559	(	(	(
559	573	IFN)-inducible	ifn)-inducible	JJ
574	581	protein	protein	NN
582	584	10	10	CD
585	586	(	(	(
586	591	IP-10	IP-10	NNP
591	592	)	)	)
593	594	(	(	(
594	595	a	a	DT
596	599	CXC	CXC	NNP
600	609	chemokine	chemokine	NN
609	610	)	)	)
611	614	was	be	VBD
615	623	markedly	markedly	RB
624	633	augmented	augment	VBN
634	636	by	by	IN
637	640	the	the	DT
641	649	IFNgamma	IFNgamma	NNP
650	659	treatment	treatment	NN
660	662	in	in	IN
663	667	PMA-	PMA-	NNP
668	670	or	or	CC
671	688	RA-differentiated	ra-differentiated	JJ
689	693	U937	u937	NN
694	699	cells	cell	NNS
699	700	,	,	,
701	704	but	but	CC
705	709	only	only	RB
710	720	marginally	marginally	RB
721	723	in	in	IN
724	740	undifferentiated	undifferentiated	JJ
741	743	or	or	CC
744	757	VitD3-treated	vitd3-treated	JJ
758	763	cells	cell	NNS
763	764	.	.	.

765	767	In	in	IN
768	776	contrast	contrast	NN
776	777	,	,	,
778	785	another	another	DT
786	795	inducible	inducible	JJ
796	800	gene	gene	NN
801	811	expression	expression	NN
812	814	of	of	IN
815	823	monocyte	monocyte	NN
824	835	chemotactic	chemotactic	JJ
836	845	protein-1	protein-1	NN
846	847	(	(	(
847	848	a	a	DT
849	851	CC	CC	NNP
852	861	chemokine	chemokine	NN
861	862	)	)	)
863	866	and	and	CC
867	870	the	the	DT
871	881	activation	activation	NN
882	884	of	of	IN
885	888	the	the	DT
889	904	transcriptional	transcriptional	JJ
905	911	factor	factor	NN
912	913	(	(	(
913	922	FcRFgamma	FcRFgamma	NNP
922	923	)	)	)
924	929	bound	bind	VBD
930	932	to	to	TO
933	936	the	the	DT
937	942	gamma	gamma	NN
943	951	response	response	NN
952	958	region	region	NN
959	963	were	be	VBD
964	973	similarly	similarly	RB
974	976	or	or	CC
977	981	less	less	RBR
982	992	abundantly	abundantly	RB
993	1000	induced	induce	VBN
1001	1003	by	by	IN
1004	1012	IFNgamma	IFNgamma	NNP
1013	1022	treatment	treatment	NN
1023	1025	in	in	IN
1026	1030	PMA-	PMA-	NNP
1031	1033	or	or	CC
1034	1051	RA-differentiated	ra-differentiated	JJ
1052	1056	U937	u937	NN
1057	1062	cells	cell	NNS
1062	1063	,	,	,
1064	1074	indicating	indicate	VBG
1075	1079	that	that	IN
1080	1089	increased	increase	VBN
1090	1095	IP-10	IP-10	NNP
1096	1100	mRNA	mRNA	NNP
1101	1110	induction	induction	NN
1111	1114	was	be	VBD
1115	1118	not	not	RB
1119	1122	due	due	JJ
1123	1125	to	to	TO
1126	1129	the	the	DT
1130	1139	augmented	augmented	JJ
1140	1147	ability	ability	NN
1148	1150	of	of	IN
1151	1154	the	the	DT
1155	1160	cells	cell	NNS
1161	1163	to	to	TO
1164	1171	respond	respond	VB
1172	1174	to	to	TO
1175	1178	the	the	DT
1179	1187	presence	presence	NN
1188	1190	of	of	IN
1191	1199	IFNgamma	IFNgamma	NNP
1199	1200	.	.	.

1201	1210	Increased	increase	VBN
1211	1221	expression	expression	NN
1222	1224	of	of	IN
1225	1241	IFNgamma-induced	ifngamma-induced	JJ
1242	1247	IP-10	IP-10	NNP
1248	1252	mRNA	mRNA	NNP
1253	1262	following	follow	VBG
1263	1266	the	the	DT
1267	1282	differentiation	differentiation	NN
1283	1285	of	of	IN
1286	1290	U937	u937	NN
1291	1296	cells	cell	NNS
1297	1300	was	be	VBD
1301	1309	mediated	mediate	VBN
1310	1317	largely	largely	RB
1318	1320	by	by	IN
1321	1330	augmented	augmented	JJ
1331	1346	transcriptional	transcriptional	JJ
1347	1355	activity	activity	NN
1356	1358	of	of	IN
1359	1362	the	the	DT
1363	1367	gene	gene	NN
1368	1371	and	and	CC
1372	1375	was	be	VBD
1376	1383	related	relate	VBN
1384	1386	to	to	TO
1387	1412	differentiation-dependent	differentiation-dependent	JJ
1413	1420	changes	change	NNS
1421	1423	of	of	IN
1424	1427	the	the	DT
1428	1436	proteins	protein	NNS
1437	1442	bound	bind	VBN
1443	1445	to	to	TO
1446	1449	IFN	ifn	NN
1450	1458	stimulus	stimulus	NN
1459	1467	response	response	NN
1468	1475	element	element	NN
1476	1477	(	(	(
1477	1481	ISRE	ISRE	NNP
1481	1482	)	)	)
1483	1486	and	and	CC
1487	1489	kB	kb	NN
1490	1495	sites	site	NNS
1495	1496	,	,	,
1497	1507	suggesting	suggest	VBG
1508	1512	that	that	IN
1513	1518	these	these	DT
1519	1526	nuclear	nuclear	JJ
1527	1535	proteins	protein	NNS
1536	1539	may	may	MD
1540	1549	determine	determine	VB
1550	1553	the	the	DT
1554	1559	IP-10	IP-10	NNP
1560	1564	mRNA	mrna	NN
1565	1577	inducibility	inducibility	NN
1578	1580	by	by	IN
1581	1589	IFNgamma	IFNgamma	NNP
1589	1590	.	.	.