0	4	Host	Host	NNP
5	12	defense	defense	NN
13	23	mechanisms	mechanism	NNS
24	33	triggered	trigger	VBN
34	36	by	by	IN
37	46	microbial	microbial	JJ
47	59	lipoproteins	lipoprotein	NNS
60	67	through	through	IN
68	77	toll-like	toll-like	JJ
78	87	receptors	receptor	NNS
87	88	.	.	.

90	93	The	the	DT
94	104	generation	generation	NN
105	107	of	of	IN
108	121	cell-mediated	cell-mediated	JJ
122	130	immunity	immunity	NN
131	138	against	against	IN
139	143	many	many	JJ
144	154	infectious	infectious	JJ
155	164	pathogens	pathogen	NNS
165	173	involves	involve	VBZ
174	177	the	the	DT
178	188	production	production	NN
189	191	of	of	IN
192	206	interleukin-12	interleukin-12	NN
207	208	(	(	(
208	213	IL-12	il-12	NN
213	214	)	)	)
214	215	,	,	,
216	217	a	a	DT
218	221	key	key	JJ
222	228	signal	signal	NN
229	231	of	of	IN
232	235	the	the	DT
236	242	innate	innate	JJ
243	249	immune	immune	JJ
250	256	system	system	NN
256	257	.	.	.

258	261	Yet	yet	RB
261	262	,	,	,
263	266	for	for	IN
267	271	many	many	JJ
272	281	pathogens	pathogen	NNS
281	282	,	,	,
283	286	the	the	DT
287	296	molecules	molecule	NNS
297	301	that	that	WDT
302	308	induce	induce	VBP
309	314	IL-12	il-12	NN
315	325	production	production	NN
326	328	by	by	IN
329	340	macrophages	macrophage	NNS
341	344	and	and	CC
345	348	the	the	DT
349	359	mechanisms	mechanism	NNS
360	362	by	by	IN
363	368	which	which	WDT
369	373	they	they	PRP
374	376	do	do	VBP
377	379	so	so	RB
380	386	remain	remain	VB
387	396	undefined	undefined	JJ
396	397	.	.	.

398	402	Here	here	RB
403	405	it	it	PRP
406	408	is	be	VBZ
409	414	shown	show	VBN
415	419	that	that	IN
420	429	microbial	microbial	JJ
430	442	lipoproteins	lipoprotein	NNS
443	446	are	be	VBP
447	453	potent	potent	JJ
454	465	stimulators	stimulator	NNS
466	468	of	of	IN
469	474	IL-12	il-12	NN
475	485	production	production	NN
486	488	by	by	IN
489	494	human	human	JJ
495	506	macrophages	macrophage	NNS
506	507	,	,	,
508	511	and	and	CC
512	516	that	that	IN
517	526	induction	induction	NN
527	529	is	be	VBZ
530	538	mediated	mediate	VBN
539	541	by	by	IN
542	551	Toll-like	toll-like	JJ
552	561	receptors	receptor	NNS
562	563	(	(	(
563	567	TLRs	TLR	NNP
567	568	)	)	)
568	569	.	.	.

570	577	Several	several	JJ
578	590	lipoproteins	lipoprotein	NNS
591	601	stimulated	stimulate	VBD
602	615	TLR-dependent	tlr-dependent	JJ
616	629	transcription	transcription	NN
630	632	of	of	IN
633	642	inducible	inducible	JJ
643	649	nitric	nitric	JJ
650	655	oxide	oxide	NN
656	664	synthase	synthase	NN
665	668	and	and	CC
669	672	the	the	DT
673	683	production	production	NN
684	686	of	of	IN
687	693	nitric	nitric	JJ
694	699	oxide	oxide	NN
699	700	,	,	,
701	702	a	a	DT
703	711	powerful	powerful	JJ
712	724	microbicidal	microbicidal	JJ
725	732	pathway	pathway	NN
732	733	.	.	.

734	744	Activation	Activation	NNP
745	747	of	of	IN
748	752	TLRs	tlr	NNS
753	755	by	by	IN
756	765	microbial	microbial	JJ
766	778	lipoproteins	lipoprotein	NNS
779	782	may	may	MD
783	791	initiate	initiate	VB
792	798	innate	innate	JJ
799	806	defense	defense	NN
807	817	mechanisms	mechanism	NNS
818	825	against	against	IN
826	836	infectious	infectious	JJ
837	846	pathogens	pathogen	NNS
846	847	.	.	.