0	1	A	a	DT
2	10	lymphoid	lymphoid	JJ
11	24	cell-specific	cell-specific	JJ
25	32	nuclear	nuclear	JJ
33	39	factor	factor	NN
40	50	containing	contain	VBG
51	61	c-Rel-like	c-rel-like	JJ
62	70	proteins	protein	NNS
71	85	preferentially	preferentially	RB
86	95	interacts	interact	VBZ
96	100	with	with	IN
101	114	interleukin-6	interleukin-6	NN
115	120	kappa	kappa	NN
121	130	B-related	b-related	JJ
131	137	motifs	motif	NNS
138	143	whose	whose	WP$
144	154	activities	activity	NNS
155	158	are	be	VBP
159	168	repressed	repress	VBN
169	171	in	in	IN
172	180	lymphoid	lymphoid	JJ
181	186	cells	cell	NNS
186	187	.	.	.

189	192	The	the	DT
193	210	proto-oncoprotein	proto-oncoprotein	NN
211	216	c-Rel	c-rel	NN
217	219	is	be	VBZ
220	221	a	a	DT
222	228	member	member	NN
229	231	of	of	IN
232	235	the	the	DT
236	243	nuclear	nuclear	JJ
244	250	factor	factor	NN
251	256	kappa	kappa	NN
257	258	B	B	NNP
259	272	transcription	transcription	NN
273	279	factor	factor	NN
280	286	family	family	NN
286	287	,	,	,
288	293	which	which	WDT
294	302	includes	include	VBZ
303	306	the	the	DT
307	310	p50	p50	NN
311	314	and	and	CC
315	318	p65	p65	NN
319	327	subunits	subunit	NNS
328	330	of	of	IN
331	338	nuclear	nuclear	JJ
339	345	factor	factor	NN
346	351	kappa	kappa	NN
352	354	B.	B.	NNP
355	357	We	we	PRP
358	362	show	show	VBP
363	367	here	here	RB
368	372	that	that	IN
373	378	c-Rel	c-rel	NN
379	384	binds	bind	VBZ
385	387	to	to	TO
388	393	kappa	kappa	NN
394	395	B	B	NNP
396	401	sites	site	NNS
402	404	as	as	IN
405	415	homodimers	homodimer	NNS
416	418	as	as	RB
419	423	well	well	RB
424	426	as	as	IN
427	439	heterodimers	heterodimer	NNS
440	444	with	with	IN
445	448	p50	p50	NN
448	449	.	.	.

450	455	These	these	DT
456	466	homodimers	homodimer	NNS
467	470	and	and	CC
471	483	heterodimers	heterodimer	NNS
484	488	show	show	VBP
489	497	distinct	distinct	JJ
498	509	DNA-binding	dna-binding	JJ
510	523	specificities	specificity	NNS
524	527	and	and	CC
528	538	affinities	affinity	NNS
539	542	for	for	IN
543	550	various	various	JJ
551	556	kappa	kappa	NN
557	558	B	b	NN
559	565	motifs	motif	NNS
565	566	.	.	.

567	569	In	in	IN
570	580	particular	particular	JJ
580	581	,	,	,
582	585	the	the	DT
586	591	c-Rel	c-rel	NN
592	601	homodimer	homodimer	NN
602	605	has	have	VBZ
606	607	a	a	DT
608	612	high	high	JJ
613	621	affinity	affinity	NN
622	625	for	for	IN
626	639	interleukin-6	interleukin-6	NN
640	641	(	(	(
641	645	IL-6	il-6	NN
645	646	)	)	)
647	650	and	and	CC
651	655	beta	beta	SYM
656	666	interferon	interferon	NN
667	672	kappa	kappa	NN
673	674	B	B	NNP
675	680	sites	site	NNS
680	681	.	.	.

682	684	In	in	IN
685	690	spite	spite	NN
691	693	of	of	IN
694	697	its	its	PRP$
698	709	association	association	NN
710	714	with	with	IN
715	718	p50	p50	NN
719	721	in	in	FW
722	727	vitro	vitro	FW
727	728	,	,	,
729	736	however	however	RB
736	737	,	,	,
738	740	we	we	PRP
741	746	found	find	VBD
747	748	a	a	DT
749	757	lymphoid	lymphoid	JJ
758	771	cell-specific	cell-specific	JJ
772	779	nuclear	nuclear	JJ
780	786	factor	factor	NN
787	789	in	in	FW
790	794	vivo	vivo	FW
795	799	that	that	WDT
800	808	contains	contain	VBZ
809	814	c-Rel	c-rel	NN
815	818	but	but	CC
819	822	not	not	RB
823	826	p50	p50	NN
827	835	epitopes	epitope	NNS
835	836	;	;	:
837	841	this	this	DT
842	848	factor	factor	NN
848	849	,	,	,
850	856	termed	term	VBN
857	861	IL-6	IL-6	NNP
862	867	kappa	kappa	NN
868	869	B	B	NNP
870	877	binding	binding	NN
878	884	factor	factor	NN
885	887	II	ii	CD
887	888	,	,	,
889	896	appears	appear	VBZ
897	899	to	to	TO
900	907	contain	contain	VB
908	911	the	the	DT
912	917	c-Rel	c-rel	NN
918	927	homodimer	homodimer	NN
928	931	and	and	CC
932	946	preferentially	preferentially	RB
947	957	recognizes	recognize	VBZ
958	965	several	several	JJ
966	970	IL-6	il-6	NN
971	976	kappa	kappa	NN
977	986	B-related	b-related	JJ
987	992	kappa	kappa	NN
993	994	B	b	NN
995	1001	motifs	motif	NNS
1001	1002	.	.	.

1003	1011	Although	although	IN
1012	1014	it	it	PRP
1015	1018	has	have	VBZ
1019	1023	been	be	VBN
1024	1034	previously	previously	RB
1035	1040	shown	show	VBN
1041	1045	that	that	IN
1046	1049	the	the	DT
1050	1054	IL-6	IL-6	NNP
1055	1060	kappa	kappa	NN
1061	1062	B	B	NNP
1063	1068	motif	motif	NN
1069	1078	functions	function	VBZ
1079	1081	as	as	IN
1082	1083	a	a	DT
1084	1090	potent	potent	JJ
1091	1101	IL-1/tumor	IL-1/tumor	NNP
1102	1110	necrosis	necrosis	NN
1111	1128	factor-responsive	factor-responsive	JJ
1129	1136	element	element	NN
1137	1139	in	in	IN
1140	1151	nonlymphoid	nonlymphoid	JJ
1152	1157	cells	cell	NNS
1157	1158	,	,	,
1159	1162	its	its	PRP$
1163	1171	activity	activity	NN
1172	1175	was	be	VBD
1176	1181	found	find	VBN
1182	1184	to	to	TO
1185	1187	be	be	VB
1188	1197	repressed	repress	VBN
1198	1200	in	in	IN
1201	1209	lymphoid	lymphoid	JJ
1210	1215	cells	cell	NNS
1216	1220	such	such	JJ
1221	1223	as	as	IN
1224	1225	a	a	DT
1226	1232	Jurkat	Jurkat	NNP
1233	1239	T-cell	T-cell	NNP
1240	1244	line	line	NN
1244	1245	.	.	.

1246	1248	We	we	PRP
1249	1253	also	also	RB
1254	1261	present	present	VBP
1262	1270	evidence	evidence	NN
1271	1275	that	that	IN
1276	1280	IL-6	IL-6	NNP
1281	1286	kappa	kappa	NN
1287	1288	B	B	NNP
1289	1296	binding	binding	NN
1297	1303	factor	factor	NN
1304	1306	II	ii	CD
1307	1316	functions	function	VBZ
1317	1319	as	as	IN
1320	1321	a	a	DT
1322	1331	repressor	repressor	NN
1332	1340	specific	specific	JJ
1341	1344	for	for	IN
1345	1349	IL-6	IL-6	NNP
1350	1355	kappa	kappa	NN
1356	1365	B-related	b-related	JJ
1366	1371	kappa	kappa	NN
1372	1373	B	b	NN
1374	1380	motifs	motif	NNS
1381	1383	in	in	IN
1384	1392	lymphoid	lymphoid	JJ
1393	1398	cells	cell	NNS
1398	1399	.	.	.