0	7	Mitogen	Mitogen	NNP
8	19	stimulation	stimulation	NN
20	22	of	of	IN
23	30	T-cells	T-cell	NNP
31	40	increases	increase	VBZ
41	46	c-Fos	c-fos	NN
47	50	and	and	CC
51	56	c-Jun	c-jun	NN
57	64	protein	protein	NN
65	71	levels	level	NNS
71	72	,	,	,
73	77	AP-1	ap-1	NN
78	85	binding	binding	NN
86	89	and	and	CC
90	94	AP-1	ap-1	NN
95	110	transcriptional	transcriptional	JJ
111	119	activity	activity	NN
119	120	.	.	.

122	124	We	we	PRP
125	129	have	have	VBP
130	138	analysed	analyse	VBN
139	142	the	the	DT
143	149	effect	effect	NN
150	152	of	of	IN
153	162	mitogenic	mitogenic	JJ
163	170	lectins	lectin	NNS
171	173	on	on	IN
174	179	c-Fos	c-fos	NN
180	183	and	and	CC
184	189	c-Jun	c-jun	NN
190	197	protein	protein	NN
198	204	levels	level	NNS
205	207	as	as	RB
208	212	well	well	RB
213	215	as	as	IN
216	218	on	on	IN
219	228	activator	activator	NN
229	238	protein-1	protein-1	NN
239	240	(	(	(
240	244	AP-1	ap-1	NN
244	245	)	)	)
246	253	binding	binding	NN
254	257	and	and	CC
258	266	enhancer	enhancer	NN
267	275	activity	activity	NN
276	278	in	in	IN
279	285	Jurkat	Jurkat	NNP
286	293	T-cells	T-cell	NNP
293	294	.	.	.

295	299	Both	both	CC
300	305	c-Fos	c-fos	NN
306	309	and	and	CC
310	315	c-Jun	c-jun	NN
316	323	protein	protein	NN
324	330	levels	level	NNS
331	335	were	be	VBD
336	345	increased	increase	VBN
346	351	after	after	IN
352	355	Con	con	NN
356	357	A	A	NNP
358	361	and	and	CC
362	365	PHA	PHA	NNP
366	377	stimulation	stimulation	NN
377	378	.	.	.

379	384	Since	since	IN
385	391	T-cell	t-cell	NN
392	403	stimulation	stimulation	NN
404	413	increases	increase	VBZ
414	418	both	both	CC
419	432	intracellular	intracellular	JJ
433	437	Ca2+	ca2+	NN
438	441	and	and	CC
442	446	cAMP	camp	NN
447	453	levels	level	NNS
454	457	and	and	CC
458	467	activates	activate	VBZ
468	475	protein	protein	NN
476	482	kinase	kinase	NNP
483	484	C	C	NNP
485	486	(	(	(
486	489	PKC	PKC	NNP
489	490	)	)	)
490	491	,	,	,
492	495	the	the	DT
496	504	possible	possible	JJ
505	516	involvement	involvement	NN
517	519	of	of	IN
520	525	these	these	DT
526	539	intracellular	intracellular	JJ
540	550	messengers	messenger	NNS
551	553	in	in	IN
554	559	c-Fos	c-fos	NN
560	563	and	and	CC
564	569	c-Jun	c-jun	NN
570	579	induction	induction	NN
580	583	was	be	VBD
584	590	tested	test	VBN
590	591	.	.	.

592	595	PMA	PMA	NNP
595	596	,	,	,
597	602	which	which	WDT
603	611	directly	directly	RB
612	621	activates	activate	VBZ
622	625	PKC	PKC	NNP
625	626	,	,	,
627	635	mimicked	mimic	VBD
636	639	the	the	DT
640	646	effect	effect	NN
647	649	of	of	IN
650	653	the	the	DT
654	661	lectins	lectin	NNS
662	664	on	on	IN
665	670	c-Fos	c-fos	NN
671	674	and	and	CC
675	680	c-Jun	c-jun	NN
680	681	,	,	,
682	685	but	but	CC
686	695	elevation	elevation	NN
696	698	of	of	IN
699	705	either	either	CC
706	719	intracellular	intracellular	JJ
720	724	Ca2+	ca2+	NN
725	727	or	or	CC
728	732	cAMP	camp	NN
733	739	levels	level	NNS
740	743	had	have	VBD
744	750	little	little	JJ
751	753	or	or	CC
754	756	no	no	DT
757	763	effect	effect	NN
763	764	.	.	.

765	768	The	the	DT
769	784	mitogen-induced	mitogen-induced	JJ
785	793	increase	increase	NN
794	796	of	of	IN
797	802	c-Fos	c-fos	NN
803	806	and	and	CC
807	812	c-Jun	c-jun	NN
813	829	immunoreactivity	immunoreactivity	NN
830	833	was	be	VBD
834	843	inhibited	inhibit	VBN
844	846	by	by	IN
847	850	H-7	H-7	NNP
850	851	,	,	,
852	853	a	a	DT
854	860	kinase	kinase	NNP
861	870	inhibitor	inhibitor	NN
871	875	with	with	IN
876	886	relatively	relatively	RB
887	891	high	high	JJ
892	903	specificity	specificity	NN
904	907	for	for	IN
908	911	PKC	PKC	NNP
911	912	,	,	,
913	916	and	and	CC
917	921	less	less	RBR
922	933	efficiently	efficiently	RB
934	936	by	by	IN
937	940	H-8	h-8	NN
940	941	,	,	,
942	943	a	a	DT
944	956	structurally	structurally	RB
957	964	related	related	JJ
965	971	kinase	kinase	NNP
972	981	inhibitor	inhibitor	NN
982	986	less	less	RBR
987	993	active	active	JJ
994	996	on	on	IN
997	1000	PKC	PKC	NNP
1000	1001	,	,	,
1002	1005	but	but	CC
1006	1010	more	more	RBR
1011	1017	active	active	JJ
1018	1020	on	on	IN
1021	1027	cyclic	cyclic	JJ
1028	1048	nucleotide-dependent	nucleotide-dependent	JJ
1049	1056	kinases	kinase	NNS
1056	1057	.	.	.

1058	1061	Con	con	NN
1062	1063	A	a	NN
1064	1075	stimulation	stimulation	NN
1076	1079	was	be	VBD
1080	1085	found	find	VBN
1086	1088	to	to	TO
1089	1097	increase	increase	VB
1098	1102	both	both	CC
1103	1110	binding	binding	NN
1111	1113	of	of	IN
1114	1118	AP-1	ap-1	NN
1119	1121	to	to	TO
1122	1125	the	the	DT
1126	1130	AP-1	ap-1	NN
1131	1140	consensus	consensus	NN
1141	1149	sequence	sequence	NN
1149	1150	,	,	,
1151	1154	TRE	TRE	NNP
1154	1155	,	,	,
1156	1159	and	and	CC
1160	1164	AP-1	ap-1	NN
1165	1173	enhancer	enhancer	NN
1174	1182	activity	activity	NN
1182	1183	,	,	,
1184	1186	in	in	IN
1187	1193	Jurkat	Jurkat	NNP
1194	1199	cells	cell	NNS
1199	1200	.	.	.

1201	1204	PMA	PMA	NNP
1205	1208	was	be	VBD
1209	1213	also	also	RB
1214	1219	found	find	VBN
1220	1222	to	to	TO
1223	1231	increase	increase	VB
1232	1235	the	the	DT
1236	1240	AP-1	ap-1	NN
1241	1249	enhancer	enhancer	NN
1250	1258	activity	activity	NN
1258	1259	,	,	,
1260	1267	whereas	whereas	IN
1268	1277	elevation	elevation	NN
1278	1280	of	of	IN
1281	1285	Ca2+	Ca2+	NNP
1286	1288	or	or	CC
1289	1293	cAMP	cAMP	NNP
1294	1297	had	have	VBD
1298	1302	only	only	RB
1303	1308	minor	minor	JJ
1309	1316	effects	effect	NNS
1316	1317	.	.	.

1318	1320	We	we	PRP
1321	1329	conclude	conclude	VBP
1330	1334	that	that	IN
1335	1346	stimulation	stimulation	NN
1347	1351	with	with	IN
1352	1361	mitogenic	mitogenic	JJ
1362	1369	lectins	lectin	NNS
1370	1372	is	be	VBZ
1373	1383	sufficient	sufficient	JJ
1384	1386	to	to	TO
1387	1395	increase	increase	VB
1396	1400	both	both	CC
1401	1406	c-Fos	c-fos	NN
1407	1410	and	and	CC
1411	1416	c-Jun	c-jun	NN
1417	1424	protein	protein	NN
1425	1431	levels	level	NNS
1431	1432	,	,	,
1433	1437	AP-1	ap-1	NN
1438	1445	binding	binding	NN
1446	1449	and	and	CC
1450	1454	AP-1	ap-1	NN
1455	1463	enhancer	enhancer	NN
1464	1472	activity	activity	NN
1473	1475	in	in	IN
1476	1482	Jurkat	Jurkat	NNP
1483	1488	cells	cell	NNS
1489	1492	and	and	CC
1493	1497	that	that	IN
1498	1502	they	they	PRP
1503	1506	act	act	VBP
1507	1510	via	via	IN
1511	1521	mechanisms	mechanism	NNS
1522	1526	that	that	WDT
1527	1532	could	could	MD
1533	1540	involve	involve	VB
1541	1544	the	the	DT
1545	1555	activation	activation	NN
1556	1558	of	of	IN
1559	1562	PKC	PKC	NNP
1562	1563	.	.	.