0 8 Specific specific JJ 9 17 NF-kappa NF-kappa NNP 18 19 B B NNP 20 28 subunits subunit NNS 29 32 act act VBP 33 35 in in IN 36 43 concert concert NN 44 48 with with IN 49 52 Tat Tat NNP 53 55 to to TO 56 65 stimulate stimulate VB 66 71 human human JJ 72 88 immunodeficiency immunodeficiency NN 89 94 virus virus NN 95 99 type type NN 100 101 1 1 CD 102 115 transcription transcription NN 115 116 . . . 118 126 NF-kappa NF-kappa NNP 127 128 B B NNP 129 131 is be VBZ 132 133 a a DT 134 141 protein protein NN 142 149 complex complex NN 150 155 which which WDT 156 165 functions function VBZ 166 168 in in IN 169 176 concert concert NN 177 181 with with IN 182 185 the the DT 186 191 tat-I tat-i NN 192 196 gene gene NN 197 204 product product NN 205 207 to to TO 208 217 stimulate stimulate VB 218 223 human human JJ 224 240 immunodeficiency immunodeficiency NN 241 246 virus virus NN 247 248 ( ( ( 248 251 HIV HIV NNP 251 252 ) ) ) 253 266 transcription transcription NN 266 267 . . . 268 270 To to TO 271 280 determine determine VB 281 288 whether whether IN 289 297 specific specific JJ 298 305 members member NNS 306 308 of of IN 309 312 the the DT 313 321 NF-kappa NF-kappa NNP 322 323 B B NNP 324 330 family family NN 331 341 contribute contribute VBP 342 344 to to TO 345 349 this this DT 350 356 effect effect NN 356 357 , , , 358 360 we we PRP 361 365 have have VBP 366 374 examined examine VBN 375 378 the the DT 379 388 abilities ability NNS 389 391 of of IN 392 401 different different JJ 402 410 NF-kappa NF-kappa NNP 411 412 B B NNP 413 421 subunits subunit NNS 422 424 to to TO 425 428 act act VB 429 433 with with IN 434 439 Tat-I Tat-I NNP 440 442 to to TO 443 452 stimulate stimulate VB 453 466 transcription transcription NN 467 469 of of IN 470 473 HIV HIV NNP 474 476 in in IN 477 483 Jurkat Jurkat NNP 484 494 T-leukemia T-leukemia NNP 495 500 cells cell NNS 500 501 . . . 502 504 We we PRP 505 509 have have VBP 510 515 found find VBN 516 520 that that IN 521 524 the the DT 525 533 p49(100) p49(100) NN 534 537 DNA dna NN 538 545 binding binding NN 546 553 subunit subunit NN 553 554 , , , 555 563 together together RB 564 568 with with IN 569 572 p65 p65 NN 572 573 , , , 574 577 can can MD 578 581 act act VB 582 584 in in IN 585 592 concert concert NN 593 597 with with IN 598 603 Tat-I Tat-I NNP 604 606 to to TO 607 616 stimulate stimulate VB 617 620 the the DT 621 631 expression expression NN 632 634 of of IN 635 642 HIV-CAT HIV-CAT NNP 643 650 plasmid plasmid NN 650 651 . . . 652 658 Little little JJ 659 665 effect effect NN 666 669 was be VBD 670 678 observed observe VBN 679 683 with with IN 684 690 50-kDa 50-kda JJ 691 696 forms form NNS 697 699 of of IN 700 704 p105 p105 NN 705 713 NF-kappa NF-kappa NNP 714 715 B B NNP 716 718 or or CC 719 722 rel rel NN 722 723 , , , 724 726 in in IN 727 738 combination combination NN 739 743 with with IN 744 747 p65 p65 NN 748 750 or or CC 751 762 full-length full-length JJ 763 768 c-rel c-rel NN 768 769 , , , 770 775 which which WDT 776 778 do do VBP 779 782 not not RB 783 792 stimulate stimulate VB 793 796 the the DT 797 800 HIV HIV NNP 801 809 enhancer enhancer NN 810 812 in in IN 813 818 these these DT 819 824 cells cell NNS 824 825 . . . 826 831 These these DT 832 840 findings finding NNS 841 848 suggest suggest VBP 849 853 that that IN 854 857 the the DT 858 869 combination combination NN 870 872 of of IN 873 881 p49(100) p49(100) NN 882 885 and and CC 886 889 p65 p65 NN 890 898 NF-kappa NF-kappa NNP 899 900 B B NNP 901 904 can can MD 905 908 act act VB 909 911 in in IN 912 919 concert concert NN 920 924 with with IN 925 928 the the DT 929 934 tat-I tat-i NN 935 939 gene gene NN 940 947 product product NN 948 950 to to TO 951 960 stimulate stimulate VB 961 964 the the DT 965 974 synthesis synthesis NN 975 977 of of IN 978 981 HIV HIV NNP 982 985 RNA RNA NNP 985 986 . . .