0 4 HIV1 hiv1 NN 5 14 infection infection NN 15 17 of of IN 18 23 human human JJ 24 33 monocytes monocyte NNS 34 37 and and CC 38 49 macrophages macrophage NNS 50 58 promotes promote VBZ 59 68 induction induction NN 69 71 or or CC 72 85 translocation translocation NN 86 88 of of IN 89 102 NF-KB-related nf-kb-related JJ 103 110 factors factor NNS 110 111 . . . 113 115 In in IN 116 120 1991 1991 CD 120 121 , , , 122 124 we we PRP 125 137 demonstrated demonstrate VBD 137 138 , , , 139 144 using use VBG 145 160 electrophoretic electrophoretic JJ 161 169 mobility mobility NN 170 175 shift shift NN 176 182 assays assay NNS 182 183 , , , 184 188 that that IN 189 190 3 3 CD 191 200 different different JJ 201 208 factors factor NNS 209 210 ( ( ( 210 216 termed term VBN 217 219 B1 B1 NNP 219 220 , , , 221 223 B2 b2 NN 224 227 and and CC 228 230 B3 b3 NN 230 231 ) ) ) 232 236 with with IN 237 245 affinity affinity NN 246 249 for for IN 250 253 the the DT 254 265 KB-enhancer KB-enhancer NNP 266 272 target target NN 273 281 sequence sequence NN 282 286 were be VBD 287 299 specifically specifically RB 300 308 detected detect VBN 309 311 in in IN 312 319 nuclear nuclear JJ 320 328 extracts extract NNS 329 333 from from IN 334 347 HIV1-infected hiv1-infected JJ 348 357 monocytes monocyte NNS 358 361 and and CC 362 373 macrophages macrophage NNS 373 374 . . . 375 378 The the DT 379 381 B2 b2 NN 382 388 factor factor NN 389 392 was be VBD 393 400 induced induce VBN 401 403 in in IN 404 407 the the DT 408 414 nuclei nucleus NNS 415 417 of of IN 418 423 these these DT 424 429 cells cell NNS 430 434 only only RB 435 439 upon upon IN 440 444 HIV1 hiv1 NN 445 454 infection infection NN 454 455 . . . 456 459 The the DT 460 462 B3 b3 NN 463 469 factor factor NN 470 473 was be VBD 474 478 only only RB 479 487 slightly slightly RB 488 495 evident evident JJ 496 498 in in IN 499 505 nuclei nucleus NNS 506 508 of of IN 509 519 uninfected uninfected JJ 520 525 cells cell NNS 526 529 but but CC 530 533 was be VBD 534 541 readily readily RB 542 552 detectable detectable JJ 553 555 in in IN 556 562 nuclei nucleus NNS 563 565 of of IN 566 574 infected infected JJ 575 584 monocytes monocyte NNS 584 585 . . . 586 589 Its its PRP$ 590 600 expression expression NN 601 609 remained remain VBD 610 614 very very RB 615 618 low low JJ 619 621 in in IN 622 628 nuclei nucleus NNS 629 631 of of IN 632 645 HIV1-infected hiv1-infected JJ 646 657 macrophages macrophage NNS 657 658 . . . 659 661 In in IN 662 666 this this DT 667 672 paper paper NN 672 673 , , , 674 676 we we PRP 677 688 demonstrate demonstrate VBP 689 693 that that IN 694 697 the the DT 698 700 B2 b2 NN 701 707 factor factor NN 708 710 is be VBZ 711 720 expressed express VBN 721 723 in in IN 724 727 the the DT 728 735 cytosol cytosol NN 736 738 of of IN 739 748 monocytes monocyte NNS 749 752 and and CC 753 764 macrophages macrophage NNS 765 767 as as IN 768 769 a a DT 770 781 DNA-binding dna-binding JJ 782 789 protein protein NN 789 790 , , , 791 801 indicating indicate VBG 802 806 that that IN 807 809 it it PRP 810 812 is be VBZ 813 816 not not RB 817 827 associated associate VBN 828 832 with with IN 833 835 an an DT 836 845 inhibitor inhibitor NN 846 847 ( ( ( 847 850 IKB IKB NNP 850 851 ) ) ) 851 852 . . . 853 857 This this DT 858 864 factor factor NN 865 873 remained remain VBD 874 883 clustered cluster VBN 884 886 in in IN 887 890 the the DT 891 898 cytosol cytosol NN 899 902 and and CC 903 906 was be VBD 907 919 translocated translocate VBN 920 922 to to TO 923 926 the the DT 927 933 nuclei nucleus NNS 934 938 only only RB 939 944 after after IN 945 949 HIV1 hiv1 NN 950 959 infection infection NN 959 960 . . . 961 964 The the DT 965 967 B3 b3 NN 968 974 factor factor NN 975 977 is be VBZ 978 986 detected detect VBN 987 989 in in IN 990 993 the the DT 994 1001 cytosol cytosol NN 1002 1006 only only RB 1007 1011 when when WRB 1012 1017 cells cell NNS 1018 1021 are be VBP 1022 1035 HIV1-infected hiv1-infected JJ 1035 1036 . . . 1037 1040 The the DT 1041 1045 role role NN 1046 1048 of of IN 1049 1053 HIV1 hiv1 NN 1054 1063 infection infection NN 1064 1066 in in IN 1067 1070 the the DT 1071 1081 expression expression NN 1082 1085 and and CC 1086 1089 the the DT 1090 1103 translocation translocation NN 1104 1106 of of IN 1107 1112 these these DT 1113 1120 factors factor NNS 1121 1123 is be VBZ 1124 1133 discussed discuss VBN 1133 1134 . . .