0 10 Expression expression NN 11 13 of of IN 14 19 c-jun c-jun NN 19 20 , , , 21 24 jun jun NN 25 26 B B NNP 27 30 and and CC 31 34 jun jun NN 35 36 D D NNP 37 52 proto-oncogenes proto-oncogene NNS 53 55 in in IN 56 61 human human JJ 62 78 peripheral-blood peripheral-blood JJ 79 91 granulocytes granulocyte NNS 91 92 . . . 94 96 We we PRP 97 101 have have VBP 102 107 found find VBN 108 112 that that IN 113 121 purified purify VBN 122 127 human human JJ 128 144 peripheral-blood peripheral-blood JJ 145 157 granulocytes granulocyte NNS 158 165 express express VBP 166 180 constitutively constitutively RB 181 192 significant significant JJ 193 199 levels level NNS 200 202 of of IN 203 218 proto-oncogenes proto-oncogene NNS 219 224 c-jun c-jun NN 224 225 , , , 226 229 jun jun NN 230 231 B B NNP 232 235 and and CC 236 239 jun jun NN 240 241 D D NNP 242 246 mRNA mRNA NNP 246 247 . . . 248 252 Upon upon IN 253 263 functional functional JJ 264 274 activation activation NN 275 277 of of IN 278 290 granulocytes granulocyte NNS 291 293 by by IN 294 295 4 4 CD 296 308 beta-phorbol beta-phorbol NN 309 321 12-myristate 12-myristate NN 322 332 13-acetate 13-acetate NN 333 334 ( ( ( 334 337 PMA PMA NNP 337 338 ) ) ) 338 339 , , , 340 343 the the DT 344 350 levels level NNS 351 353 of of IN 354 359 c-jun c-jun NN 359 360 , , , 361 364 jun jun NN 365 366 B B NNP 367 370 and and CC 371 374 jun jun NN 375 376 D D NNP 377 388 transcripts transcript NNS 389 393 were be VBD 394 403 increased increase VBN 403 404 . . . 405 408 The the DT 409 414 three three CD 415 418 jun jun NN 419 424 genes gene NNS 425 431 showed show VBD 432 433 a a DT 434 441 similar similar JJ 442 446 time time NN 447 453 course course NN 454 456 in in IN 457 462 their their PRP$ 463 472 induction induction NN 473 475 by by IN 476 479 PMA PMA NNP 479 480 , , , 481 488 maximal maximal JJ 489 493 mRNA mrna NN 494 500 levels level NNS 501 506 being be VBG 507 514 reached reach VBN 515 520 after after IN 521 523 60 60 CD 524 527 min min NN 528 530 of of IN 531 540 induction induction NN 540 541 . . . 542 547 These these DT 548 555 results result NNS 556 563 suggest suggest VBP 564 568 that that IN 569 579 expression expression NN 580 582 of of IN 583 588 c-jun c-jun NN 588 589 , , , 590 593 jun jun NN 594 595 B B NNP 596 599 and and CC 600 603 jun jun NN 604 605 D D NNP 606 611 genes gene NNS 612 617 might might MD 618 620 be be VB 621 629 involved involve VBN 630 632 in in IN 633 641 terminal terminal JJ 642 653 granulocyte granulocyte NN 654 669 differentiation differentiation NN 670 672 or or CC 673 675 in in IN 676 686 regulating regulate VBG 687 698 granulocyte granulocyte NN 699 712 functionality functionality NN 712 713 . . .