0 16 Interferon-gamma Interferon-gamma NNP 17 20 and and CC 21 24 the the DT 25 31 sexual sexual JJ 32 42 dimorphism dimorphism NN 43 45 of of IN 46 58 autoimmunity autoimmunity NN 58 59 . . . 61 64 The the DT 65 71 sexual sexual JJ 72 82 difference difference NN 83 85 in in IN 86 89 the the DT 90 99 incidence incidence NN 100 102 of of IN 103 113 autoimmune autoimmune JJ 114 122 diseases disease NNS 123 126 has have VBZ 127 135 remained remain VBN 136 138 an an DT 139 145 enigma enigma NN 146 149 for for IN 150 154 many many JJ 155 160 years year NNS 160 161 . . . 162 164 In in IN 165 168 the the DT 169 180 examination examination NN 181 183 of of IN 184 187 the the DT 188 197 induction induction NN 198 200 of of IN 201 213 autoimmunity autoimmunity NN 214 216 in in IN 217 227 transgenic transgenic JJ 228 232 mice mouse NNS 232 233 , , , 234 242 evidence evidence NN 243 246 has have VBZ 247 251 been be VBN 252 260 obtained obtain VBN 261 268 further further RBR 269 280 implicating implicate VBG 281 284 the the DT 285 295 lymphokine lymphokine NN 296 312 interferon-gamma interferon-gamma NN 313 315 in in IN 316 319 the the DT 320 328 etiology etiology NN 329 331 of of IN 332 344 autoimmunity autoimmunity NN 344 345 . . . 346 349 Sex sex NN 350 357 steroid steroid NN 358 368 regulation regulation NN 369 371 of of IN 372 375 the the DT 376 386 production production NN 387 389 of of IN 390 394 this this DT 395 403 molecule molecule NN 403 404 , , , 405 407 as as RB 408 412 well well RB 413 415 as as IN 416 421 other other JJ 422 431 cytokines cytokine NNS 431 432 , , , 433 436 may may MD 437 441 help help VB 442 449 explain explain VB 450 453 the the DT 454 469 gender-specific gender-specific JJ 470 481 differences difference NNS 482 484 in in IN 485 488 the the DT 489 495 immune immune JJ 496 502 system system NN 502 503 , , , 504 513 including include VBG 514 526 autoimmunity autoimmunity NN 526 527 . . .