0	7	Protein	protein	NN
8	14	kinase	kinase	NNP
15	16	C	C	NNP
17	19	is	be	VBZ
20	23	not	not	RB
24	25	a	a	DT
26	36	downstream	downstream	JJ
37	45	effector	effector	NN
46	48	of	of	IN
49	55	p21ras	p21ras	NN
56	58	in	in	IN
59	68	activated	activate	VBN
69	70	T	t	NN
71	76	cells	cell	NNS
76	77	.	.	.

79	82	The	the	DT
83	86	aim	aim	NN
87	89	of	of	IN
90	94	this	this	DT
95	102	present	present	JJ
103	108	study	study	NN
109	112	was	be	VBD
113	115	to	to	TO
116	127	investigate	investigate	VB
128	131	the	the	DT
132	136	role	role	NN
137	139	of	of	IN
140	147	protein	protein	NN
148	154	kinase	kinase	NNP
155	156	C	C	NNP
157	158	(	(	(
158	161	PKC	PKC	NNP
161	162	)	)	)
162	163	,	,	,
164	174	downstream	downstream	RB
175	177	of	of	IN
178	184	p21ras	p21ras	NN
184	185	,	,	,
186	188	in	in	IN
189	199	activating	activate	VBG
200	213	interleukin-2	interleukin-2	NN
214	215	(	(	(
215	219	IL-2	il-2	NN
219	220	)	)	)
221	225	gene	gene	NN
226	236	expression	expression	NN
236	237	.	.	.

238	240	It	it	PRP
241	244	has	have	VBZ
245	249	been	be	VBN
250	258	reported	report	VBN
259	263	that	that	IN
264	267	PKC	PKC	NNP
268	270	is	be	VBZ
271	273	an	an	DT
274	282	effector	effector	NN
283	285	of	of	IN
286	292	p21ras	p21ras	NN
293	295	in	in	IN
296	297	T	t	NN
298	303	cells	cell	NNS
303	304	.	.	.

305	309	Data	Data	NNP
310	312	is	be	VBZ
313	322	presented	present	VBN
322	323	,	,	,
324	329	using	use	VBG
330	333	the	the	DT
334	340	potent	potent	JJ
341	344	and	and	CC
345	354	selective	selective	JJ
355	358	PKC	PKC	NNP
359	368	inhibitor	inhibitor	NN
369	371	Ro	Ro	NNP
372	379	31-8425	31-8425	CD
380	383	and	and	CC
384	393	transient	transient	JJ
394	404	expression	expression	NN
405	407	of	of	IN
408	409	a	a	DT
410	424	constitutively	constitutively	RB
425	431	active	active	JJ
432	435	ras	ras	NN
436	442	mutant	mutant	NN
442	443	,	,	,
444	449	which	which	WDT
450	457	clearly	clearly	RB
458	463	shows	show	VBZ
464	468	that	that	IN
469	472	PKC	PKC	NNP
473	475	is	be	VBZ
476	479	not	not	RB
480	490	downstream	downstream	JJ
491	493	of	of	IN
494	500	p21ras	p21ras	NN
501	503	in	in	IN
504	507	the	the	DT
508	517	induction	induction	NN
518	520	of	of	IN
521	526	NF-AT	NF-AT	NNP
527	530	and	and	CC
531	535	AP-1	ap-1	NN
536	551	transcriptional	transcriptional	JJ
552	560	activity	activity	NN
561	564	and	and	CC
565	567	in	in	IN
568	571	the	the	DT
572	582	expression	expression	NN
583	585	of	of	IN
586	590	IL-2	il-2	NN
591	593	in	in	IN
594	599	human	human	JJ
600	606	Jurkat	Jurkat	NNP
607	608	T	t	NN
609	614	cells	cell	NNS
614	615	.	.	.

616	624	Reporter	reporter	NN
625	629	gene	gene	NN
630	641	experiments	experiment	NNS
642	654	demonstrated	demonstrate	VBD
655	659	that	that	IN
660	668	NF-kappa	NF-kappa	NNP
669	670	B	B	NNP
671	686	transcriptional	transcriptional	JJ
687	695	activity	activity	NN
696	698	is	be	VBZ
699	702	not	not	RB
703	711	affected	affect	VBN
712	714	by	by	IN
715	725	expression	expression	NN
726	728	of	of	IN
729	738	activated	activate	VBN
739	745	p21ras	p21ras	NN
745	746	.	.	.

747	750	The	the	DT
751	760	signaling	signaling	NN
761	769	pathways	pathway	NNS
770	779	involving	involve	VBG
780	783	PKC	PKC	NNP
784	794	activation	activation	NN
794	795	,	,	,
796	803	calcium	calcium	NN
804	816	mobilization	mobilization	NN
817	820	and	and	CC
821	824	ras	ras	NN
825	835	activation	activation	NN
836	843	combine	combine	VBP
844	846	to	to	TO
847	854	provide	provide	VB
855	858	the	the	DT
859	868	necessary	necessary	JJ
869	879	components	component	NNS
880	883	for	for	IN
884	894	production	production	NN
895	897	of	of	IN
898	902	IL-2	il-2	NN
903	909	during	during	IN
910	911	T	t	NN
912	916	cell	cell	NN
917	927	activation	activation	NN
927	928	.	.	.