0	8	Sequence	sequence	NN
9	17	analysis	analysis	NN
18	21	and	and	CC
22	32	expression	expression	NN
33	35	in	in	IN
36	44	cultured	culture	VBN
45	56	lymphocytes	lymphocyte	NNS
57	59	of	of	IN
60	63	the	the	DT
64	69	human	human	JJ
70	74	FOSB	FOSB	NNP
75	79	gene	gene	NN
80	81	(	(	(
81	85	G0S3	G0S3	NNP
85	86	)	)	)
86	87	.	.	.

89	93	G0S3	G0S3	NNP
94	96	is	be	VBZ
97	98	a	a	DT
99	105	member	member	NN
106	108	of	of	IN
109	110	a	a	DT
111	114	set	set	NN
115	117	of	of	IN
118	126	putative	putative	JJ
127	132	G0/G1	g0/g1	NN
133	139	switch	switch	NN
140	150	regulatory	regulatory	JJ
151	156	genes	gene	NNS
157	158	(	(	(
158	161	G0S	G0S	NNP
162	167	genes	gene	NNS
167	168	)	)	)
169	177	selected	select	VBN
178	180	by	by	IN
181	190	screening	screen	VBG
191	195	cDNA	cdna	NN
196	205	libraries	library	NNS
206	214	prepared	prepare	VBN
215	219	from	from	IN
220	225	human	human	JJ
226	231	blood	blood	NN
232	243	mononuclear	mononuclear	JJ
244	249	cells	cell	NNS
250	258	cultured	culture	VBN
259	262	for	for	IN
263	264	2	2	CD
265	267	hr	hr	NN
268	272	with	with	IN
273	279	lectin	lectin	NN
280	283	and	and	CC
284	297	cycloheximide	cycloheximide	NN
297	298	.	.	.

299	302	The	the	DT
303	311	sequence	sequence	NN
312	317	shows	show	VBZ
318	322	high	high	JJ
323	331	homology	homology	NN
332	336	with	with	IN
337	340	the	the	DT
341	347	murine	murine	JJ
348	352	FOSB	FOSB	NNP
353	357	gene	gene	NN
357	358	,	,	,
359	364	which	which	WDT
365	372	encodes	encode	VBZ
373	374	a	a	DT
375	384	component	component	NN
385	387	of	of	IN
388	391	the	the	DT
392	395	AP1	ap1	NN
396	411	transcriptional	transcriptional	JJ
412	421	regulator	regulator	NN
421	422	.	.	.

423	433	Comparison	comparison	NN
434	436	of	of	IN
437	441	cDNA	cdna	NN
442	445	and	and	CC
446	453	genomic	genomic	JJ
454	463	sequences	sequence	NNS
464	471	reveals	reveal	VBZ
472	473	a	a	DT
474	480	4-exon	4-exon	NN
481	490	structure	structure	NN
491	505	characteristic	characteristic	JJ
506	508	of	of	IN
509	512	the	the	DT
513	516	FOS	FOS	NNP
517	523	family	family	NN
524	526	of	of	IN
527	532	genes	gene	NNS
532	533	.	.	.

534	541	Freshly	freshly	RB
542	550	isolated	isolate	VBN
551	556	cells	cell	NNS
557	561	show	show	VBP
562	566	high	high	JJ
567	573	levels	level	NNS
574	576	of	of	IN
577	586	FOSB/G0S3	FOSB/G0S3	NNP
587	590	and	and	CC
591	599	FOS/G0S7	fos/g0s7	NN
600	605	mRNAs	mrna	NNS
605	606	,	,	,
607	612	which	which	WDT
613	620	decline	decline	VBP
621	628	rapidly	rapidly	RB
629	635	during	during	IN
636	646	incubation	incubation	NN
647	649	in	in	IN
650	657	culture	culture	NN
658	664	medium	medium	NN
664	665	.	.	.

666	669	The	the	DT
670	678	kinetics	kinetic	NNS
679	681	of	of	IN
682	692	expression	expression	NN
693	700	suggest	suggest	VBP
701	705	that	that	IN
706	709	the	the	DT
710	714	high	high	JJ
715	722	initial	initial	JJ
723	729	levels	level	NNS
730	733	are	be	VBP
734	740	caused	cause	VBN
741	743	by	by	IN
744	747	the	the	DT
748	757	isolation	isolation	NN
758	767	procedure	procedure	NN
767	768	,	,	,
769	772	and	and	CC
773	775	do	do	VBP
776	779	not	not	RB
780	787	reflect	reflect	VB
788	800	constitutive	constitutive	JJ
801	811	expression	expression	NN
811	812	.	.	.

813	815	In	in	IN
816	821	cells	cell	NNS
822	834	preincubated	preincubate	VBN
835	838	for	for	IN
839	840	a	a	DT
841	844	day	day	NN
844	845	,	,	,
846	852	levels	level	NNS
853	855	of	of	IN
856	859	FOS	FOS	NNP
860	864	mRNA	mRNA	NNP
865	870	reach	reach	VBP
871	872	a	a	DT
873	880	maximum	maximum	NN
881	883	20	20	CD
884	887	min	min	NN
888	893	after	after	IN
894	897	the	the	DT
898	906	addition	addition	NN
907	909	of	of	IN
910	916	lectin	lectin	NN
917	920	and	and	CC
921	928	decline	decline	VBP
929	931	to	to	TO
932	939	control	control	NN
940	946	levels	level	NNS
947	951	over	over	IN
952	955	the	the	DT
956	960	next	next	JJ
961	962	3	3	CD
963	966	hr.	hr.	NN
967	973	Levels	level	NNS
974	976	of	of	IN
977	981	FOSB	FOSB	NNP
982	986	mRNA	mRNA	NNP
987	992	reach	reach	VBP
993	994	a	a	DT
995	1002	maximum	maximum	JJ
1003	1005	40	40	CD
1006	1009	min	min	NN
1010	1015	after	after	IN
1016	1019	the	the	DT
1020	1028	addition	addition	NN
1029	1031	of	of	IN
1032	1038	lectin	lectin	NN
1039	1042	and	and	CC
1043	1050	decline	decline	VBP
1051	1053	to	to	TO
1054	1061	control	control	NN
1062	1068	levels	level	NNS
1069	1073	over	over	IN
1074	1077	the	the	DT
1078	1082	next	next	JJ
1083	1084	6	6	CD
1085	1087	hr	hr	NN
1087	1088	.	.	.

1089	1091	In	in	IN
1092	1099	freshly	freshly	RB
1100	1108	isolated	isolate	VBN
1109	1114	cells	cell	NNS
1114	1115	,	,	,
1116	1120	both	both	CC
1121	1124	FOS	FOS	NNP
1125	1128	and	and	CC
1129	1133	FOSB	FOSB	NNP
1134	1139	mRNAs	mrna	NNS
1140	1148	increase	increase	VBP
1149	1161	dramatically	dramatically	RB
1162	1164	in	in	IN
1165	1173	response	response	NN
1174	1176	to	to	TO
1177	1180	the	the	DT
1181	1188	protein	protein	NN
1189	1198	synthesis	synthesis	NN
1199	1208	inhibitor	inhibitor	NN
1209	1222	cycloheximide	cycloheximide	NN
1222	1223	.	.	.

1224	1226	In	in	IN
1227	1239	preincubated	preincubated	JJ
1240	1245	cells	cell	NNS
1245	1246	,	,	,
1247	1250	the	the	DT
1251	1264	cycloheximide	cycloheximide	NN
1265	1273	response	response	NN
1274	1276	is	be	VBZ
1277	1286	decreased	decrease	VBN
1286	1287	,	,	,
1288	1298	especially	especially	RB
1299	1301	in	in	IN
1302	1305	the	the	DT
1306	1310	case	case	NN
1311	1313	of	of	IN
1314	1318	FOSB	FOSB	NNP
1318	1319	.	.	.

1320	1325	These	these	DT
1326	1337	differences	difference	NNS
1338	1340	in	in	IN
1341	1351	expression	expression	NN
1352	1354	of	of	IN
1355	1358	FOS	FOS	NNP
1359	1362	and	and	CC
1363	1367	FOSB	FOSB	NNP
1368	1375	suggest	suggest	VBP
1376	1385	different	different	JJ
1386	1391	roles	role	NNS
1392	1395	and	and	CC
1396	1406	regulation	regulation	NN
1406	1407	.	.	.

1408	1415	Regions	region	NNS
1416	1418	of	of	IN
1419	1422	low	low	JJ
1423	1427	base	base	NN
1428	1443	order-dependent	order-dependent	JJ
1444	1453	stem-loop	stem-loop	JJ
1454	1463	potential	potential	NN
1464	1466	in	in	IN
1467	1470	the	the	DT
1471	1477	region	region	NN
1478	1480	of	of	IN
1481	1484	the	the	DT
1485	1489	gene	gene	NN
1490	1493	are	be	VBP
1494	1501	defined	define	VBN
1501	1502	.	.	.

1503	1508	These	these	DT
1509	1517	indicate	indicate	VBP
1518	1523	where	where	WRB
1524	1528	base	base	NN
1529	1534	order	order	NN
1535	1538	has	have	VBZ
1539	1543	been	be	VBN
1544	1551	adapted	adapt	VBN
1552	1555	for	for	IN
1556	1564	purposes	purpose	NNS
1565	1570	other	other	JJ
1571	1575	than	than	IN
1576	1585	stem-loop	stem-loop	JJ
1586	1595	stability	stability	NN
1596	1597	(	(	(
1597	1601	e.g.	e.g.	FW
1601	1602	,	,	,
1603	1611	encoding	encode	VBG
1612	1620	proteins	protein	NNS
1621	1623	or	or	CC
1624	1628	gene	gene	NN
1629	1639	regulation	regulation	NN
1639	1640	)	)	)
1640	1641	.	.	.

1642	1649	Regions	region	NNS
1650	1652	of	of	IN
1653	1656	low	low	JJ
1657	1666	potential	potential	NN
1667	1669	in	in	IN
1670	1671	a	a	DT
1672	1679	68.5-kb	68.5-kb	JJ
1680	1687	genomic	genomic	JJ
1688	1695	segment	segment	NN
1696	1706	containing	contain	VBG
1707	1710	the	the	DT
1711	1715	FOSB	FOSB	NNP
1716	1720	gene	gene	NN
1721	1728	suggest	suggest	VBP
1729	1733	that	that	IN
1734	1737	the	the	DT
1738	1747	potential	potential	NN
1748	1751	may	may	MD
1752	1756	help	help	VB
1757	1763	locate	locate	VB
1764	1769	genes	gene	NNS
1770	1772	in	in	IN
1773	1782	uncharted	uncharted	JJ
1783	1786	DNA	dna	NN
1787	1796	sequences	sequence	NNS
1796	1797	.	.	.