0	16	alpha-Tocopheryl	alpha-tocopheryl	NN
17	26	succinate	succinate	NN
27	35	inhibits	inhibit	VBZ
36	45	monocytic	monocytic	JJ
46	50	cell	cell	NN
51	59	adhesion	adhesion	NN
60	62	to	to	TO
63	74	endothelial	endothelial	JJ
75	80	cells	cell	NNS
81	83	by	by	IN
84	95	suppressing	suppress	VBG
96	104	NF-kappa	NF-kappa	NNP
105	106	B	B	NNP
107	119	mobilization	mobilization	NN
119	120	.	.	.

122	125	The	the	DT
126	135	adherence	adherence	NN
136	138	of	of	IN
139	148	monocytes	monocyte	NNS
149	151	to	to	TO
152	161	activated	activate	VBN
162	173	endothelium	endothelium	NN
174	176	is	be	VBZ
177	179	an	an	DT
180	185	early	early	JJ
186	191	event	event	NN
192	194	in	in	IN
195	208	atherogenesis	atherogenesis	NN
208	209	.	.	.

210	217	Because	because	IN
218	230	antioxidants	antioxidant	NNS
231	235	have	have	VBP
236	240	been	be	VBN
241	251	considered	consider	VBN
252	254	to	to	TO
255	257	be	be	VB
258	260	of	of	IN
261	280	antiatherosclerotic	antiatherosclerotic	JJ
281	290	potential	potential	NN
290	291	,	,	,
292	294	we	we	PRP
295	307	investigated	investigate	VBD
308	311	the	the	DT
312	319	effects	effect	NNS
320	322	of	of	IN
323	339	alpha-tocopherol	alpha-tocopherol	NN
340	341	(	(	(
341	344	TCP	TCP	NNP
344	345	)	)	)
346	349	and	and	CC
350	353	its	its	PRP$
354	361	acetate	acetate	NN
362	365	and	and	CC
366	375	succinate	succinate	NN
376	382	esters	ester	NNS
383	385	on	on	IN
386	394	monocyte	monocyte	NN
395	403	adhesion	adhesion	NN
404	406	to	to	TO
407	426	cytokine-stimulated	cytokine-stimulated	JJ
427	432	human	human	JJ
433	442	umbilical	umbilical	JJ
443	447	vein	vein	NN
448	459	endothelial	endothelial	JJ
460	465	cells	cell	NNS
466	467	(	(	(
467	472	HUVEC	HUVEC	NNP
472	473	)	)	)
473	474	.	.	.

475	486	Endothelial	endothelial	JJ
487	492	cells	cell	NNS
493	497	were	be	VBD
498	505	treated	treat	VBN
506	510	with	with	IN
511	514	TCP	TCP	NNP
514	515	,	,	,
516	532	alpha-tocopherol	alpha-tocopherol	NN
533	540	acetate	acetate	NN
541	542	(	(	(
542	545	TCP	TCP	NNP
546	553	acetate	acetate	NN
553	554	)	)	)
554	555	,	,	,
556	558	or	or	CC
559	575	alpha-tocopheryl	alpha-tocopheryl	NN
576	585	succinate	succinate	NN
586	587	(	(	(
587	590	TCP	TCP	NNP
591	600	succinate	succinate	NN
600	601	)	)	)
602	608	before	before	IN
609	620	stimulation	stimulation	NN
621	625	with	with	IN
626	631	tumor	tumor	NN
632	640	necrosis	necrosis	NN
641	653	factor-alpha	factor-alpha	NN
654	655	(	(	(
655	664	TNF-alpha	TNF-alpha	NNP
664	665	;	;	:
666	668	10	10	CD
669	673	U/ml	U/ml	NNP
673	674	,	,	,
675	676	6	6	CD
677	678	h	h	NN
678	679	)	)	)
680	682	or	or	CC
683	696	interleukin-1	interleukin-1	NN
697	701	beta	beta	SYM
702	703	(	(	(
703	707	IL-1	il-1	NN
708	712	beta	beta	NN
712	713	;	;	:
714	716	10	10	CD
717	721	U/ml	U/ml	NNP
721	722	,	,	,
723	724	6	6	CD
725	726	h	h	NN
726	727	)	)	)
727	728	.	.	.

729	748	Cytokine-stimulated	cytokine-stimulated	JJ
749	753	cell	cell	NN
754	761	surface	surface	NN
762	772	expression	expression	NN
773	775	of	of	IN
776	784	vascular	vascular	JJ
785	789	cell	cell	NN
790	798	adhesion	adhesion	NN
799	809	molecule-1	molecule-1	NN
810	811	(	(	(
811	817	VCAM-1	VCAM-1	NNP
817	818	,	,	,
819	824	CD106	CD106	NNP
824	825	)	)	)
826	829	and	and	CC
830	840	E-selectin	E-selectin	NNP
841	842	(	(	(
842	848	ELAM-1	ELAM-1	NNP
848	849	,	,	,
850	855	CD62E	CD62E	NNP
855	856	)	)	)
856	857	,	,	,
858	861	but	but	CC
862	865	not	not	RB
866	868	of	of	IN
869	882	intercellular	intercellular	JJ
883	891	adhesion	adhesion	NN
892	902	molecule-1	molecule-1	NN
903	904	(	(	(
904	910	ICAM-1	ICAM-1	NNP
910	911	,	,	,
912	916	CD54	CD54	NNP
916	917	)	)	)
917	918	,	,	,
919	922	was	be	VBD
923	928	time-	time-	NN
929	932	and	and	CC
933	949	dose-dependently	dose-dependently	RB
950	959	inhibited	inhibit	VBN
960	962	by	by	IN
963	966	TCP	TCP	NNP
967	976	succinate	succinate	NN
977	980	but	but	CC
981	984	not	not	RB
985	987	by	by	IN
988	991	TCP	TCP	NNP
992	994	or	or	CC
995	998	TCP	TCP	NNP
999	1006	acetate	acetate	NN
1006	1007	.	.	.

1008	1011	TCP	TCP	NNP
1012	1021	succinate	succinate	NN
1022	1023	(	(	(
1023	1026	200	200	CD
1027	1033	microM	microM	NNP
1033	1034	,	,	,
1035	1037	24	24	CD
1038	1039	h	h	NN
1039	1040	)	)	)
1041	1048	reduced	reduce	VBD
1049	1060	TNF-induced	tnf-induced	JJ
1061	1067	VCAM-1	VCAM-1	NNP
1068	1071	and	and	CC
1072	1082	E-selectin	E-selectin	NNP
1083	1093	expression	expression	NN
1094	1098	from	from	IN
1099	1100	a	a	DT
1101	1109	specific	specific	JJ
1110	1114	mean	mean	JJ
1115	1127	fluorescence	fluorescence	NN
1128	1137	intensity	intensity	NN
1138	1140	of	of	IN
1141	1144	151	151	CD
1145	1148	+/-	+/-	SYM
1149	1151	28	28	CD
1152	1154	to	to	TO
1155	1157	12	12	CD
1158	1161	+/-	+/-	CC
1162	1163	4	4	CD
1164	1172	channels	channel	NNS
1173	1176	and	and	CC
1177	1181	from	from	IN
1182	1185	225	225	CD
1186	1189	+/-	+/-	SYM
1190	1192	38	38	CD
1193	1195	to	to	TO
1196	1198	79	79	CD
1199	1202	+/-	+/-	CC
1203	1205	21	21	CD
1206	1214	channels	channel	NNS
1214	1215	,	,	,
1216	1228	respectively	respectively	RB
1228	1229	.	.	.

1230	1239	Succinate	Succinate	NNP
1240	1245	alone	alone	RB
1246	1249	had	have	VBD
1250	1252	no	no	DT
1253	1259	effect	effect	NN
1259	1260	.	.	.

1261	1270	Decreased	decrease	VBN
1271	1279	adhesion	adhesion	NN
1280	1288	molecule	molecule	NN
1289	1299	expression	expression	NN
1300	1303	was	be	VBD
1304	1314	associated	associate	VBN
1315	1319	with	with	IN
1320	1321	a	a	DT
1322	1331	reduction	reduction	NN
1332	1334	of	of	IN
1335	1344	monocytic	monocytic	JJ
1345	1349	cell	cell	NN
1350	1358	adhesion	adhesion	NN
1358	1359	.	.	.

1360	1363	TCP	TCP	NNP
1364	1373	succinate	succinate	NN
1374	1375	(	(	(
1375	1377	20	20	CD
1378	1384	microM	microM	NNP
1384	1385	,	,	,
1386	1388	72	72	CD
1389	1390	h	h	NN
1390	1391	)	)	)
1391	1392	,	,	,
1393	1396	but	but	CC
1397	1400	not	not	RB
1401	1404	TCP	TCP	NNP
1405	1406	(	(	(
1406	1409	200	200	CD
1410	1416	microM	microM	NNP
1416	1417	,	,	,
1418	1420	72	72	CD
1421	1422	h	h	NN
1422	1423	)	)	)
1423	1424	,	,	,
1425	1432	reduced	reduce	VBD
1433	1438	U-937	u-937	NN
1439	1443	cell	cell	NN
1444	1452	adhesion	adhesion	NN
1453	1455	to	to	TO
1456	1476	TNF-alpha-stimulated	tnf-alpha-stimulated	JJ
1477	1478	(	(	(
1478	1480	10	10	CD
1481	1485	U/ml	U/ml	NNP
1485	1486	,	,	,
1487	1488	6	6	CD
1489	1490	h	h	NN
1490	1491	)	)	)
1492	1497	HUVEC	HUVEC	NNP
1498	1500	by	by	IN
1501	1503	30	30	CD
1503	1504	%	%	NN
1505	1506	(	(	(
1506	1507	P	p	NN
1508	1509	<	<	JJR
1510	1515	0.025	0.025	CD
1515	1516	)	)	)
1517	1520	and	and	CC
1521	1523	to	to	TO
1524	1528	IL-1	il-1	NN
1529	1544	beta-stimulated	beta-stimulated	JJ
1545	1550	HUVEC	HUVEC	NNP
1551	1553	by	by	IN
1554	1556	56	56	CD
1556	1557	%	%	NN
1558	1559	(	(	(
1559	1560	P	p	NN
1561	1562	<	<	JJR
1563	1568	0.010	0.010	CD
1568	1569	)	)	)
1569	1570	.	.	.

1571	1586	Electrophoretic	electrophoretic	JJ
1587	1601	mobility-shift	mobility-shift	JJ
1602	1608	assays	assay	NNS
1609	1611	of	of	IN
1612	1617	HUVEC	HUVEC	NNP
1618	1625	nuclear	nuclear	JJ
1626	1634	proteins	protein	NNS
1635	1643	revealed	reveal	VBD
1644	1645	a	a	DT
1646	1654	decrease	decrease	NN
1655	1657	in	in	IN
1658	1678	TNF-alpha-stimulated	tnf-alpha-stimulated	JJ
1679	1686	nuclear	nuclear	JJ
1687	1699	factor-kappa	factor-kappa	NN
1700	1701	B	B	NNP
1702	1703	(	(	(
1703	1711	NF-kappa	NF-kappa	NNP
1712	1713	B	B	NNP
1713	1714	)	)	)
1715	1725	activation	activation	NN
1726	1731	after	after	IN
1732	1744	pretreatment	pretreatment	NN
1745	1747	of	of	IN
1748	1753	HUVEC	HUVEC	NNP
1754	1758	with	with	IN
1759	1762	TCP	TCP	NNP
1763	1772	succinate	succinate	NN
1773	1776	but	but	CC
1777	1780	not	not	RB
1781	1785	with	with	IN
1786	1789	TCP	TCP	NNP
1789	1790	,	,	,
1791	1794	TCP	TCP	NNP
1795	1802	acetate	acetate	NN
1802	1803	,	,	,
1804	1806	or	or	CC
1807	1816	succinate	succinate	NN
1817	1822	alone	alone	RB
1822	1823	.	.	.

1824	1826	In	in	IN
1827	1837	conclusion	conclusion	NN
1837	1838	,	,	,
1839	1841	we	we	PRP
1842	1853	demonstrate	demonstrate	VBP
1854	1858	that	that	IN
1859	1862	the	the	DT
1863	1870	vitamin	vitamin	NN
1871	1872	E	e	NN
1873	1883	derivative	derivative	JJ
1884	1887	TCP	TCP	NNP
1888	1897	succinate	succinate	NN
1898	1906	prevents	prevent	VBZ
1907	1916	monocytic	monocytic	JJ
1917	1921	cell	cell	NN
1922	1930	adhesion	adhesion	NN
1931	1933	to	to	TO
1934	1953	cytokine-stimulated	cytokine-stimulated	JJ
1954	1965	endothelial	endothelial	JJ
1966	1971	cells	cell	NNS
1972	1974	by	by	IN
1975	1985	inhibiting	inhibit	VBG
1986	1989	the	the	DT
1990	2000	activation	activation	NN
2001	2003	of	of	IN
2004	2012	NF-kappa	NF-kappa	NNP
2013	2014	B	B	NNP
2014	2015	,	,	,
2016	2023	further	further	RB
2024	2035	emphasizing	emphasize	VBG
2036	2039	the	the	DT
2040	2059	antiatherosclerotic	antiatherosclerotic	JJ
2060	2069	potential	potential	NN
2070	2072	of	of	IN
2073	2078	lipid	lipid	NN
2079	2086	soluble	soluble	JJ
2087	2099	antioxidants	antioxidant	NNS
2099	2100	.	.	.