0 8 Temporal temporal JJ 9 16 control control NN 17 19 of of IN 20 23 IgH IgH NNP 24 28 gene gene NN 29 39 expression expression NN 40 42 in in IN 43 53 developing develop VBG 54 55 B B NNP 56 61 cells cell NNS 62 64 by by IN 65 68 the the DT 69 70 3 3 CD 70 71 ’ ' SYM 72 77 locus locus NN 78 85 control control NN 86 92 region region NN 92 93 . . . 95 98 The the DT 99 108 suggested suggest VBN 109 114 roles role NNS 115 117 of of IN 118 121 the the DT 122 132 downstream downstream JJ 133 134 3 3 CD 134 135 ’ ' SYM 136 143 regions region NNS 144 150 acting act VBG 151 153 as as IN 154 155 a a DT 156 161 Locus Locus NNP 162 169 Control Control NNP 170 176 Region Region NNP 177 178 ( ( ( 178 181 LCR LCR NNP 181 182 ) ) ) 182 183 , , , 184 188 have have VBP 189 196 allowed allow VBN 197 208 comparisons comparison NNS 209 211 to to TO 212 214 be be VB 215 219 made make VBN 220 227 between between IN 228 231 the the DT 232 242 regulation regulation NN 243 245 of of IN 246 249 the the DT 250 253 IgH IgH NNP 254 259 locus locus NN 260 264 with with IN 265 270 other other JJ 271 276 model model NN 277 284 systems system NNS 285 290 whose whose WP$ 291 295 gene gene NN 296 306 expression expression NN 307 309 is be VBZ 310 318 governed govern VBN 319 321 by by IN 322 325 LCR LCR NNP 326 334 activity activity NN 334 335 . . . 336 340 Here here RB 341 343 we we PRP 344 353 summarize summarize VBP 354 357 the the DT 358 368 importance importance NN 369 371 of of IN 372 375 the the DT 376 379 IgH IgH NNP 380 385 3’LCR 3'LCR NNP 386 389 and and CC 390 393 its its PRP$ 394 402 putative putative JJ 403 413 functional functional JJ 414 418 role role NN 419 421 in in IN 422 425 IgH IgH NNP 426 430 gene gene NN 431 441 expression expression NN 442 445 and and CC 446 453 compare compare VB 454 456 it it PRP 457 461 with with IN 462 465 the the DT 466 471 5’LCR 5'LCR NNP 472 482 regulatory regulatory JJ 483 489 region region NN 490 492 of of IN 493 496 the the DT 497 502 human human JJ 503 514 beta-globin beta-globin NN 515 520 locus locus NN 520 521 . . .