0	3	The	the	DT
4	9	small	small	JJ
10	21	GTP-binding	gtp-binding	JJ
22	29	protein	protein	NN
30	33	Rho	Rho	NNP
34	45	potentiates	potentiate	VBZ
46	50	AP-1	ap-1	NN
51	64	transcription	transcription	NN
65	67	in	in	IN
68	69	T	t	NN
70	75	cells	cell	NNS
75	76	.	.	.

78	81	The	the	DT
82	85	Rho	Rho	NNP
86	92	family	family	NN
93	95	of	of	IN
96	101	small	small	JJ
102	113	GTP-binding	gtp-binding	JJ
114	122	proteins	protein	NNS
123	125	is	be	VBZ
126	134	involved	involve	VBN
135	137	in	in	IN
138	141	the	the	DT
142	152	regulation	regulation	NN
153	155	of	of	IN
156	168	cytoskeletal	cytoskeletal	JJ
169	178	structure	structure	NN
178	179	,	,	,
180	184	gene	gene	NN
185	198	transcription	transcription	NN
198	199	,	,	,
200	208	specific	specific	JJ
209	213	cell	cell	NN
214	218	fate	fate	NN
219	230	development	development	NN
230	231	,	,	,
232	235	and	and	CC
236	250	transformation	transformation	NN
250	251	.	.	.

252	254	We	we	PRP
255	266	demonstrate	demonstrate	VBP
267	269	in	in	IN
270	274	this	this	DT
275	281	report	report	NN
282	286	that	that	IN
287	301	overexpression	overexpression	NN
302	304	of	of	IN
305	307	an	an	DT
308	317	activated	activated	JJ
318	322	form	form	NN
323	325	of	of	IN
326	329	Rho	Rho	NNP
330	338	enhances	enhance	VBZ
339	343	AP-1	ap-1	NN
344	352	activity	activity	NN
353	355	in	in	IN
356	362	Jurkat	Jurkat	NNP
363	364	T	t	NN
365	370	cells	cell	NNS
371	373	in	in	IN
374	377	the	the	DT
378	386	presence	presence	NN
387	389	of	of	IN
390	397	phorbol	phorbol	NN
398	407	myristate	myristate	NN
408	415	acetate	acetate	NN
416	417	(	(	(
417	420	PMA	PMA	NNP
420	421	)	)	)
421	422	,	,	,
423	426	but	but	CC
427	436	activated	activate	VBD
437	440	Rho	Rho	NNP
441	442	(	(	(
442	448	V14Rho	V14Rho	NNP
448	449	)	)	)
450	453	has	have	VBZ
454	460	little	little	JJ
461	463	or	or	CC
464	466	no	no	DT
467	473	effect	effect	NN
474	476	on	on	IN
477	481	NFAT	NFAT	NNP
481	482	,	,	,
483	488	Oct-1	Oct-1	NNP
488	489	,	,	,
490	493	and	and	CC
494	503	NF-kappaB	NF-kappaB	NNP
504	512	enhancer	enhancer	NN
513	520	element	element	NN
521	531	activities	activity	NNS
532	537	under	under	IN
538	545	similar	similar	JJ
546	556	conditions	condition	NNS
556	557	.	.	.

558	572	Overexpression	overexpression	NN
573	575	of	of	IN
576	577	a	a	DT
578	584	V14Rho	V14Rho	NNP
585	594	construct	construct	NN
595	604	incapable	incapable	JJ
605	607	of	of	IN
608	616	membrane	membrane	NN
617	629	localization	localization	NN
630	631	(	(	(
631	635	CAAX	CAAX	NNP
636	643	deleted	delete	VBN
643	644	)	)	)
645	654	abolishes	abolish	VBZ
655	666	PMA-induced	pma-induced	JJ
667	671	AP-1	ap-1	NN
672	687	transcriptional	transcriptional	JJ
688	698	activation	activation	NN
698	699	.	.	.

700	703	The	the	DT
704	710	effect	effect	NN
711	713	of	of	IN
714	717	Rho	Rho	NNP
718	720	on	on	IN
721	725	AP-1	ap-1	NN
726	728	is	be	VBZ
729	740	independent	independent	JJ
741	743	of	of	IN
744	747	the	the	DT
748	765	mitogen-activated	mitogen-activated	JJ
766	773	protein	protein	NN
774	780	kinase	kinase	NNP
781	788	pathway	pathway	NN
788	789	,	,	,
790	792	as	as	IN
793	794	a	a	DT
795	812	dominant-negative	dominant-negative	JJ
813	816	MEK	mek	NN
817	820	and	and	CC
821	822	a	a	DT
823	826	MEK	MEK	NNP
827	836	inhibitor	inhibitor	NN
837	838	(	(	(
838	845	PD98059	PD98059	NNP
845	846	)	)	)
847	850	did	do	VBD
851	854	not	not	RB
855	861	affect	affect	VB
862	873	Rho-induced	rho-induced	JJ
874	878	AP-1	ap-1	NN
879	887	activity	activity	NN
887	888	.	.	.

889	895	V14Rho	V14Rho	NNP
896	901	binds	bind	VBZ
902	910	strongly	strongly	RB
911	913	to	to	TO
914	921	protein	protein	NN
922	928	kinase	kinase	NNP
929	935	Calpha	Calpha	NNP
936	937	(	(	(
937	945	PKCalpha	PKCalpha	NNP
945	946	)	)	)
947	949	in	in	FW
950	954	vivo	vivo	FW
954	955	;	;	:
956	963	however	however	RB
963	964	,	,	,
965	973	deletion	deletion	NN
974	976	of	of	IN
977	980	the	the	DT
981	985	CAAX	CAAX	NNP
986	990	site	site	NN
991	993	on	on	IN
994	1000	V14Rho	V14Rho	NNP
1001	1009	severely	severely	RB
1010	1020	diminished	diminish	VBD
1021	1025	this	this	DT
1026	1037	association	association	NN
1037	1038	.	.	.

1039	1047	Evidence	evidence	NN
1048	1051	for	for	IN
1052	1053	a	a	DT
1054	1058	role	role	NN
1059	1062	for	for	IN
1063	1071	PKCalpha	PKCalpha	NNP
1072	1074	as	as	IN
1075	1077	an	an	DT
1078	1086	effector	effector	NN
1087	1089	of	of	IN
1090	1093	Rho	Rho	NNP
1094	1097	was	be	VBD
1098	1106	obtained	obtain	VBN
1107	1109	by	by	IN
1110	1113	the	the	DT
1114	1125	observation	observation	NN
1126	1130	that	that	IN
1131	1143	coexpression	coexpression	NN
1144	1146	of	of	IN
1147	1150	the	the	DT
1151	1161	N-terminal	n-terminal	JJ
1162	1168	domain	domain	NN
1169	1171	of	of	IN
1172	1180	PKCalpha	PKCalpha	NNP
1181	1188	blocked	block	VBD
1189	1192	the	the	DT
1193	1200	effects	effect	NNS
1201	1203	of	of	IN
1204	1213	activated	activate	VBN
1214	1217	Rho	Rho	NNP
1218	1222	plus	plus	CC
1223	1226	PMA	PMA	NNP
1227	1229	on	on	IN
1230	1234	AP-1	ap-1	NN
1235	1250	transcriptional	transcriptional	JJ
1251	1259	activity	activity	NN
1259	1260	.	.	.

1261	1266	These	these	DT
1267	1271	data	datum	NNS
1272	1279	suggest	suggest	VBP
1280	1284	that	that	IN
1285	1288	Rho	Rho	NNP
1289	1300	potentiates	potentiate	VBZ
1301	1305	AP-1	ap-1	NN
1306	1319	transcription	transcription	NN
1320	1326	during	during	IN
1327	1333	T-cell	t-cell	NN
1334	1344	activation	activation	NN
1344	1345	.	.	.