0	13	Transcription	Transcription	NNP
14	20	factor	factor	NN
21	30	NF-kappaB	nf-kappab	NN
31	41	regulation	regulation	NN
42	44	of	of	IN
45	50	renal	renal	JJ
51	59	fibrosis	fibrosis	NN
60	66	during	during	IN
67	75	ureteral	ureteral	JJ
76	87	obstruction	obstruction	NN
87	88	.	.	.

90	102	Irrespective	irrespective	JJ
103	105	of	of	IN
106	109	the	the	DT
110	118	etiology	etiology	NN
118	119	,	,	,
120	124	many	many	JJ
125	131	kidney	kidney	NN
132	140	diseases	disease	NNS
141	147	result	result	VBP
148	150	in	in	IN
151	163	inflammation	inflammation	NN
164	167	and	and	CC
168	176	fibrosis	fibrosis	NN
177	179	of	of	IN
180	183	the	the	DT
184	202	tubulointerstitium	tubulointerstitium	NN
202	203	,	,	,
204	208	with	with	IN
209	212	the	the	DT
213	223	subsequent	subsequent	JJ
224	228	loss	loss	NN
229	231	of	of	IN
232	237	renal	renal	JJ
238	246	function	function	NN
246	247	.	.	.

248	250	To	to	TO
251	259	initiate	initiate	VB
260	263	any	any	DT
264	271	disease	disease	NN
272	279	process	process	NN
280	282	or	or	CC
283	286	for	for	IN
287	290	any	any	DT
291	298	disease	disease	NN
299	306	process	process	NN
307	309	to	to	TO
310	318	progress	progress	VB
318	319	,	,	,
320	325	there	there	EX
326	330	must	must	MD
331	333	be	be	VB
334	341	changes	change	NNS
342	344	in	in	IN
345	348	the	the	DT
349	362	transcription	transcription	NN
363	365	of	of	IN
366	371	genes	gene	NNS
372	378	within	within	IN
379	382	the	the	DT
383	391	affected	affect	VBN
392	398	tissue	tissue	NN
398	399	.	.	.

400	403	The	the	DT
404	411	nuclear	nuclear	JJ
412	424	factor-kappa	factor-kappa	NN
425	426	B	B	NNP
427	428	(	(	(
428	437	NF-kappaB	NF-kappaB	NNP
437	438	)	)	)
439	445	family	family	NN
446	448	of	of	IN
449	462	transcription	transcription	NN
463	470	factors	factor	NNS
471	480	regulates	regulate	VBZ
481	486	genes	gene	NNS
487	495	involved	involve	VBN
496	498	in	in	IN
499	511	inflammation	inflammation	NN
511	512	,	,	,
513	517	cell	cell	NN
518	531	proliferation	proliferation	NN
531	532	,	,	,
533	536	and	and	CC
537	541	cell	cell	NN
542	557	differentiation	differentiation	NN
557	558	.	.	.

559	563	This	this	DT
564	570	review	review	NN
571	580	discusses	discuss	VBZ
581	584	the	the	DT
585	594	NF-kappaB	NF-kappaB	NNP
595	608	transcription	transcription	NN
609	615	factor	factor	NN
616	622	family	family	NN
623	625	in	in	IN
626	633	general	general	JJ
634	637	and	and	CC
638	641	the	the	DT
642	653	association	association	NN
654	656	of	of	IN
657	666	NF-kappaB	NF-kappaB	NNP
667	677	activation	activation	NN
678	682	with	with	IN
683	701	cellular/molecular	cellular/molecular	JJ
702	708	events	event	NNS
709	711	of	of	IN
712	717	renal	renal	JJ
718	730	inflammation	inflammation	NN
731	734	and	and	CC
735	743	fibrosis	fibrosis	NN
743	744	.	.	.