0	12	Intranuclear	intranuclear	JJ
13	21	targeted	target	VBN
22	30	delivery	delivery	NN
31	33	of	of	IN
34	44	functional	functional	JJ
45	54	NF-kappaB	nf-kappab	NN
55	57	by	by	IN
58	60	70	70	CD
61	64	kDa	kda	NN
65	69	heat	heat	NN
70	75	shock	shock	NN
76	83	protein	protein	NN
83	84	.	.	.

86	89	The	the	DT
90	92	70	70	CD
93	96	kDa	kda	NN
97	101	heat	heat	NN
102	107	shock	shock	NN
108	115	protein	protein	NN
116	117	(	(	(
117	122	Hsp70	Hsp70	NNP
122	123	)	)	)
124	126	is	be	VBZ
127	128	a	a	DT
129	135	highly	highly	RB
136	145	conserved	conserve	VBN
145	146	,	,	,
147	157	ubiquitous	ubiquitous	JJ
158	165	protein	protein	NN
166	174	involved	involve	VBN
175	177	in	in	IN
178	189	chaperoning	chaperon	VBG
190	198	proteins	protein	NNS
199	201	to	to	TO
202	209	various	various	JJ
210	218	cellular	cellular	JJ
219	229	organelles	organelle	NNS
229	230	.	.	.

231	235	Here	here	RB
236	238	we	we	PRP
239	243	show	show	VBP
244	248	that	that	IN
249	253	when	when	WRB
254	259	added	add	VBN
260	271	exogenously	exogenously	RB
272	274	to	to	TO
275	280	cells	cell	NNS
280	281	,	,	,
282	287	Hsp70	Hsp70	NNP
288	290	is	be	VBZ
291	298	readily	readily	RB
299	307	imported	import	VBN
308	312	into	into	IN
313	317	both	both	CC
318	329	cytoplasmic	cytoplasmic	JJ
330	333	and	and	CC
334	341	nuclear	nuclear	JJ
342	354	compartments	compartment	NNS
355	357	in	in	IN
358	359	a	a	DT
360	378	cell-type-specific	cell-type-specific	JJ
379	386	fashion	fashion	NN
386	387	.	.	.

388	390	We	we	PRP
391	400	exploited	exploit	VBD
401	405	this	this	DT
406	413	ability	ability	NN
414	416	of	of	IN
417	422	Hsp70	Hsp70	NNP
423	425	to	to	TO
426	433	deliver	deliver	VB
434	443	NF-kappaB	NF-kappaB	NNP
443	444	,	,	,
445	446	a	a	DT
447	450	key	key	JJ
451	466	transcriptional	transcriptional	JJ
467	476	regulator	regulator	NN
477	479	of	of	IN
480	492	inflammatory	inflammatory	JJ
493	502	responses	response	NNS
502	503	.	.	.

504	506	We	we	PRP
507	518	demonstrate	demonstrate	VBP
519	523	that	that	IN
524	525	a	a	DT
526	532	fusion	fusion	NN
533	540	protein	protein	NN
541	549	composed	compose	VBN
550	552	of	of	IN
553	554	a	a	DT
555	565	C-terminal	c-terminal	JJ
566	571	Hsp70	Hsp70	NNP
572	579	peptide	peptide	NN
580	583	and	and	CC
584	587	the	the	DT
588	591	p50	p50	NN
592	599	subunit	subunit	NN
600	602	of	of	IN
603	612	NF-kappaB	NF-kappaB	NNP
613	616	was	be	VBD
617	625	directed	direct	VBN
626	630	into	into	IN
631	634	the	the	DT
635	642	nucleus	nucleus	NN
643	645	of	of	IN
646	651	cells	cell	NNS
651	652	,	,	,
653	658	could	could	MD
659	663	bind	bind	VB
664	667	DNA	dna	NN
668	680	specifically	specifically	RB
680	681	,	,	,
682	685	and	and	CC
686	695	activated	activate	VBN
696	703	Igkappa	Igkappa	NNP
704	714	expression	expression	NN
715	718	and	and	CC
719	727	TNFalpha	TNFalpha	NNP
728	738	production	production	NN
738	739	.	.	.

740	742	We	we	PRP
743	752	therefore	therefore	RB
753	760	propose	propose	VBP
761	765	that	that	IN
766	771	Hsp70	hsp70	NN
772	775	can	can	MD
776	778	be	be	VB
779	783	used	use	VBN
784	786	as	as	IN
787	788	a	a	DT
789	796	vehicle	vehicle	NN
797	800	for	for	IN
801	817	intracytoplasmic	intracytoplasmic	JJ
818	821	and	and	CC
822	834	intranuclear	intranuclear	JJ
835	843	delivery	delivery	NN
844	846	of	of	IN
847	855	proteins	protein	NNS
856	858	or	or	CC
859	862	DNA	dna	NN
863	865	to	to	TO
866	874	modulate	modulate	VB
875	879	gene	gene	NN
880	890	expression	expression	NN
891	894	and	and	CC
895	902	thereby	thereby	RB
903	910	control	control	VBP
911	917	immune	immune	JJ
918	927	responses	response	NNS
927	928	.	.	.